Acetone is added to a polysaccharide as a swelling agent and then the polysaccharide is esterified with an acid anhydride. What role does acetone play here? What is meant by swelling? There are no other catalysts added to the reaction mix. Will the reaction occur?
Acetone can undergo acetalization under the reaction condition.
Ok..thank you. But i read a paper where they have used acetone as a swelling agent and they have shown through ft-ir that the esterification of polysaccharide has occurred. Is the. Acetylated one a byproduct?
Acetals are not detected in the carbonyl region of esters (~1740cm-1). Even though it is formed, it is not identified
Thanks Ramesha..... I'm performing the reaction around 50 deg C. The reaction medium will be slightly acidic.... Will this still lead to acetalization?... This byproduct would be removable by washing with the appropriate solvent right? And yet my desired pdt would be formed....
Acetone can undergo several reactions:
1- with the alcohol groups of your carbohydrate to yield acetonides.
2- Perhaps with acetic anhydride to afford the enol acetate (base needed?).