If I,m going to asses reliability of new tool developed by me to estimate the risk of atherosclerosis through a cross sectional study how to calculate sample size avoid confounders make randomization
Use online sample size calculator but you need prevalence rate of atherosclerosis. Take confidence of interval 95% and error 5% (0.05)
Hi Arwa
I strongly suggest you get some advice from a biostatistician. You need more help than can be provided here.
First, it is necessary to establish if reliability is only to be determined or validity is also necessary, the sample depends on the objective of the study and on the nature of the variables of the developed tool. I suggest to review the objectives and consult a statistician.
A good book Health Measurement Scales: A practical guide to their development and use.
JP
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