Totally agree with you dear Dr. Manal ❤

They really have a horrible side effects 😕

Agreed

Dear Dr. Mubashir Ali Rather Thank you so much, really thanks.

Some artificial sweeteners may have some side effects and cause unpleasant symptoms, such as headaches, depression, and seizures.

Animal studies have proven that artificial sweeteners cause weight gain, brain tumors, bladder cancer and many other health hazards.

Article Sugar substitutes: Health controversy over perceived benefits

Totally agree with you dear Dr. Manal ❤

They really have a horrible side effects 😕

Also, see the RG link below.

Article The Potential Toxicity of Artificial Sweeteners

It is produced to prevent the toxic effects of sugar. However, it has toxic effects on health. Its toxic effects are generally observational. There are not enough randomized studies.

Please see the related link:

Article Artificial sweeteners: Safe or unsafe?

Article Artificial sweeteners as a sugar substitute: Are they really safe?

A significant proportion of artificial sweeteners produced by a chemical processing technology may have a much more negative effect on health than the sugar they replace in food products. The carcinogenic, carcinogenic effects of artificial sweeteners have already been detected. On the other hand, there are methods for producing natural sweeteners from some plants classified as herbal plants containing natural, organic sweeteners, much sweeter than the popular sugar (sucrose). Unfortunately, mass-produced artificial sweeteners are often not based on these natural raw materials.

Regards,

Dariusz Prokopowicz

Dear Dr. Hassan Izzeddin Sarsak Thank you so much, really thanks.

Dear Dr. Arvind Singh Thank you so much, really thanks.

Dear Dr. Diana A. Ali Thank you so much, really thanks.

Dear Dr. Dariusz Prokopowicz Thank you so much, really thanks.

Dear Dr. Serdar Kalemci Thank you so much, really thanks.

Please have a look at this link

https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/artificial-sweeteners/art-20046936

Dear Dr. Lamia Al-Naama Thank you so much, really thanks.

Dear Dr. Terri Purvis

These sweeteners contribute to an increase in insulin resistance

Dear dr. Manal These sweeteners contribute to an increase in insulin resistance

Dear Dr. Omar Aljubouri Thank you so much, really thanks.

Dear Dr. Mohammed Alobaidy Thank you so much, really thanks.

These artificial sweeteners may cause terrifying health problems, especially when consumed in excess for a long time.

Dear Dr Manal Hadi Kanaan. Artificial sweeteners, like many other food additives are not free from risk and harm to health. Many are associated with adverse, and potentially serious health consequences.

like many other food additives are not free from risk and harm to health. Many are associated with adverse, and potentially serious health consequences.

Manal Hadi Kanaan

https://www.researchgate.net/publication/286502199_Artificial_sweeteners_and_sugar_substitutes_-some_properties_and_potential_health_benefits_and_risks

Dear Dr. Talal A. Zari Thank you so much, really thanks.

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Dear Dr. Nirmala S.V.S.G Thank you so much, really thanks.

One side effect of artificial sweeteners on the brain and taste is they can change how we taste the food. A minuscule amount produces a sweet taste comparable to that of a much higher volume of sugar, without comparable calories. Overstimulation of sugar receptors from frequent use of these hyper-intense sweeteners may limit tolerance for more complex tastes. So, people who routinely use artificial sweeteners may start to find less intensely sweet foods, such as fruit, less appealing and unsweet foods, like vegetables, unpalatable. In other words, regular consumption of artificial sweeteners can detract you from healthy and nutritious foods. As well as, they are highly processed, often with chemicals, and have minimal to no studies showing that they are safe for long term human consumption.

https://www.justdatesyrup.com/blogs/research/the-truth-on-artificial-sweeteners-zero-sugar-at-a-bitter-cost

Potential Concerns of Artificial Sweeteners

Artificial sweeteners are often used instead of sucrose to sweeten foods and beverages. One of the most popular of them, saccharin, in 2000 was removed from the U.S. National Toxicology Program's Report on Carcinogens, where it had been listed since 1981 (suspected to cause urinary bladder cancer) as an anticipated human carcinogen. However, high doses of saccharin cause bladder stones comprised of sodium saccharin and bladder cancer in male rats.

Studies of another sweetener, aspartame, which was suspected of increasing the risk for human brain tumors, did not confirm the association. Currently three artificial sweeteners – acesulfame potassium, Sucralose, and Neotame – are authorized for use in food in the United States: More than 100 safety studies showed no evidence that they cause cancer in humans. Recent studies concluded that cyclamate, banned in 1969 by the U.S. Food and Drug Administration (FDA) as possibly associated with human urinary bladder cancer, was not a carcinogen.

https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/artificial-sweeteners

https://www.health.harvard.edu/blog/artificial-sweeteners-sugar-free-but-at-what-cost-201207165030.

Artificial sweeteners have been scrutinized intensely for decades. Critics of artificial sweeteners say that they cause a variety of health problems, including cancer. That's largely because of studies dating to the 1970s that linked the artificial sweetener saccharin to bladder cancer in laboratory rats. https://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/artificial-sweeteners/art-20046936

Artificial sweeteners sometimes have negative effects on the body and brain that sugars do not. Our brains, stomach microbes, and pancreases process artificial and real sugars differently—which can cause us to eat more, gain more weight, and have a harder time digesting the real sugars that our bodies need. https://kids.frontiersin.org/article/10.3389/frym.2019.00051

Consuming artificial sweeteners can be enjoyable but doing so in excess (or as a replacement for sugar entirely) is dangerous, because of the differences in how our brains and bodies process these two substances, and the potential negative health consequences of over-consuming either one. Over-consumption of artificial sugars alters the body’s ability to process real sugar, through changes in the gut microbiota and insulin levels. This can lead to negative health outcomes such as type 2 diabetes—while at the same time making people crave more sugar, making them want to eat more food, and potentially causing them to gain more weight.

https://kids.frontiersin.org/article/10.3389/frym.2019.00051

The body reacts to artificial sweeteners differently than it does to sugar — the healthy bacteria that live in the gut, for example, change when these compounds are around — and the consequences might be both surprising and unwelcome, especially for children. https://time.com/the-trouble-with-sugar-free-kids/

Dear Dr. Aqeel yousif Alshukri Thank you so much, really thanks.

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Artificial sweeteners also cause dependency syndrome where someone mouth will be itching to taste the sweeteners and they become restless until they get it.

Dear Dr. Kiprotich Kiptum Thank you so much, really thanks.

Dear Manal Hadi Kanaan

You have initiated a very relevant discussion, as the cumulative use of synthetic sweeteners has increased tremendously in the past few decades, yet there are no appreciable effects on the prevalence of the two most important lifestyle diseases (obesity and diabetes) that these are supposed to prevent.

The scientific community has begun to realise the potential long-term health risks of processed or ultra-processed foods where synthetic sweeteners are commonly used. The problem is that conducting long-term health risk studies is extremely difficult due to several confounding factors. So we will have to depend on the long-standing experience of human consumption to realize the health hazards of sweeteners.

Till then, a cautious advice emphasizing on "consumption in moderation" can be given.

Dear Dr. Devi Dayal Thank you so much, really thanks.

Studies are continuing due to people's concern about the use of artificial sweeteners and given so much evidence, it seems too early to recommend sugary drinks as a complete substitute for sugar.

Dear Dr. Ahmed Saeed Mohmed Thank you so much, really thanks.

Artificial sweeteners (AS) are non-nutritive food additives that provide sweetness with few or no calories. They can be extracted from natural sources or chemically made. They are mainly incorporated in many food products, drinks, and medicines. Only six AS (sucralose, aspartame, aspartame, acesulfame, neotame, and advantame) are granted US FDA approval. However, the way the body responds to these AS is very complex and uncertain. Despite strong warnings from principal health authorities, like AHA, and ADA, AS are frequently used to combat overweight, obesity, cardiometabolic syndrome, and diabetes, as well as all risk factors for cardiovascular disease. In this context, the issue of cancer is not resolved yet nor that of the effect of AS on the human molecular metabolomic and genomic aspects. The question of AS doses and safety for various age and physiological groups is also not resolved. In addition to their concerns on these diseases and issues, AS ruin appetite, energy intake, diet quality and density, and food habits. Nowadays, it is well-accepted that there is no solid scientific evidence to support the AS use as a routine dietary regimen. Evidence of the long-term use of AS and their impact on human health is controversial. The AS consumption is increasing at an alarming rate and accounts for one-third of the global market. Thus, it is evident that the health cost of using AS is very high and truly exceeds that of sugar. In this regard, It remains to address one of the basics of Nutrition and Dietetics and how a healthful or natural diet is defined: Healthful or natural diet is composed of natural, whole, and minimally processed foods or food products without food additives or supplements.

Dear Dr. Mousa Numan Ahmad Thank you so much, really thanks.

Dear Dr. Manal Hadi Kanaan , Important question and but, the answer is more important for the society. So, thanks for initiating a discussion on this topic. Artificial sweeteners are not good for health. In fact, the evolution tells/ shows that whatever we eat should have some utility/meaning. If we (animals like elephant, birds etc) take mud or wet soil, it denotes deficiency of certain important elements required for the body. So, anything we eat should be helpful to the body function. The fibers (based on my knowledge) do not have any calorific value but play an important role. I fully endorse the points put forth by Dr. Arvind Singh. and Dr. Mousa Numan Ahmad. They have made certain valid points worth everyone's attention. Warm regards Yoganandnan G

Dear Dr. Yoganandan G. Thank you so much, really thanks.