Are there any tools that can integrate the missed cleavage derived phosphosites diffusion so that we can achieve a precise?

04 April 2019 1 2K Report

In the data sheet from PD or Maxquant, there are many phosphopeptides which are derived from missed cleavage. That means one phosphosite is distributed to different peptides due to the missed cleavage. Different phosphopeptides containg the same phosphosites due to the missed cleavage. Are there any tools or softares or R packages that can integrate the missed cleavage derived phosphosites diffusion so that we can achieve a precise quantification of phosphosites?

Michael Plank

Hi,

I am currently working on such a tool. It will only visualize the different peptides contributing to a site and handles one user-specified phosphosite at a time. If that`s still helpful, I am happy to send you a beta-version.

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