I have not  come across any such trial. However, I can not deny that such strategy might just work. Because, a decade ago we had published this article and bubble never burst.

"J Negat Results Biomed. 2005 Mar 23;4:3.

The "Statinth" wonder of the world: a panacea for all illnesses or a bubble about to burst.

Shafiq N1, Malhotra S, Pandhi P, Grover A."

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079931/

Dear Alì,  your interesting answer raises some problems. Often, the adverse events of statins such as myalgia or rabdomyolysis or liver toxicity are due to individual sensitivty to the drug. My anwer is: are there proven evidences that avoiding daily assumption may reduce these effects. A second question arises from the hypothesized escavanger action of high doses of statind in diffuse chronic coronaropathy. In this case it is obvious that a soft administation cannot be of help. Fianlly, what are the alterantive options to satins. Ezetimibide has shown to be very effective in loweriing LDL cholestrol and curing non-alcoholic steatohepatitis (MOZART TRIAL, Hepatology 2014 Dec 6. doi: 10.1002/hep.27647). 

I would like to see larger scale trials (and comparative graphs) before forming an opinion, but alternate day dosing does look like a possibility, based on the limited AJM data, and an extended secondary phase pharmacologic profile. Actually, I am already conducting a personal trial, as I experience myalgia occasionally on 20 mg/day simvastatin, and have reduced it to alternate days. Great question, Anil. 

Dear Anil,

There are studies on alternative day statins versus daily statin therapy, some of the studies proved that, the alternative regimen therapy  is equally efficacious as  daily regime. But  the ADR like Myopathy, myalgia is less likely to observe in alternate day regime. Again it may vary from drug to drug, I  could not find a meta analysis for the same. Let me try for some good studies. 

Wish you all the best