I'm a retired research chemist/physicist with Parkinson's disease and I've been working on upregulating Nrf2 with sulforaphane to fight oxidative stress.
The results I achieved on my PD and with a group of 8 people with PD have shown that sulforaphane strongly attenuated non-motor symptoms especially fatigue and lack of motivation, suggesting that the first target for Nrf2 seems to be mitochondria. I am not an expert in this subject and I would like to reach out to research groups and Parkinson's disease specialists to discuss how to take this idea further.
You can find the background here :
https://wp.me/pc57vK-1o
And a preprint I have written on RG here:
https://www.researchgate.net/deref/http%3A%2F%2Fdx.doi.org%2F10.13140%2FRG.2.2.21776.43529%2F1?_sg%5B0%5D=kBzth1rfHVPs90_iOo3imbsNXVH6sRTguWcBiNWL12tDLz1PNQbsHriCxD3J8KqOh_x9wa5qK7NL6_hUlYz-BzlnYQ.JSTdcyKA5S1eXqc7LbM79Ek1ACtUTv44hsbD4bFiifFwxN6PGEvCcC45xHKgho96cM6fmsJ__Bju8FXvDU9C_w
I have been using sulforaphane for the treatment of my age related macular degeneration. After three years my vision has not deteriorated further.
Macular degenaration is strongly related to oxidative stress.
We must suppose that sulforaphane is an interesting drug to prevent tissue deterioration due to oxidative stress.
Hello Tomas, that's interesting. How do you prepare your sulforaphane and what dose do you use?
I have been using 400 micrograms twice a day. Brand: Swanson.
I have had the drug checked at the University and they confirmed it is 87% pure sulforaphane. Not the 99% the lab says. But is good enough for me.
- Badges
- Science topic
- Similar topics
- Chemistry
- Pharmacology
- Medical Pharmacology
- Clinical Pharmacology