Are drugs that are susceptible to first pass metabolism readily excreted?

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Can other standards be used to generate IRF file instead of LaB6,Si etc.,,, for Rietveld Refinement?

Hi, my research involves in ZnO synthesis. I have performed rietveld refinement of my samples and obtain a good fit using Fullprof suite software. However to obtain the crystallite size, the IRF...

07 July 2024 3,526 3 View

How to calculate corrosion rate from potentiodynamic polarization test data for dissimilar welds?

we need surface area, corrosion current, equivalent weight and density of the metal involved for corrosion rate calculation in mm/year (lets say). For dissimilar metal welds, how can we measure...

30 June 2024 5,943 2 View

How to convert energy count spectrum into 2D/3D image?

Respected researcher, I want to know that is there any way or one can help in generating a 2D/3D image using the energy count spectrum of from backscatter methods. How can I design such an...

29 June 2024 10,023 1 View

What is Academic Research Paper?

I do a research about Non-Verbal Communication: Gestures and Body Language in Classroom.

18 June 2024 8,737 1 View

Can i deduce the presence of surface states based on my XPS data?

In my XPS spectral, i detected oxygen group bonded to carbon and in my zinc spectral (note : my sample is ZnO) ...there are two valent zinc species available, (which is unsual as my previous...

17 June 2024 3,888 2 View

Action research design is Quantitative Studies or Qualitative Studies?

14 June 2024 1,684 1 View

How should I interpret this moderation analysis (PROCESS Macro)?

Hi there! I was wondering how I should go about interpreting the following data. I am currently investigating the moderating role of working memory (continuous) on the relationship between...

07 June 2024 1,473 0 View

I need help?

Is there anyone to tell me the scientific name of this mushroom?

03 June 2024 464 5 View

How Through Silicon Vias (TSV) simulated in Silvaco?

How can we simulate TSV in the Silvaco example? Exactly, I need the instructions for the attachments file. Best regards.

29 May 2024 1,638 1 View

Best firm level database for south Asian firms?

best firm level database for south Asian firms?

28 May 2024 3,424 0 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

What are some diseases that are caused by overactivity of enzymes?

I want to choose a resarch topic regarding enzyme inhibition. So I did my research and found out most of the diseases that originate from enzymes were actually caused by the "deficiency" of...

30 July 2024 2,483 5 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

How can microbial engineering techniques be used to enhance the functionality and efficacy of probiotics ?

through genetic modification or metabolic engineering? Is it helpful, good for health ?

22 July 2024 7,811 4 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

MTT assay - 6 well plate?

Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...

13 July 2024 9,783 1 View

How to convince decision makers to adjust the legislation to allow opening of drug consumption rooms?

In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...

08 July 2024 8,903 1 View