Dear colleagues,
Im looking for your advice regarding tools (preferably curated) able to link metabolic pathways (e.g., KEGG IDs) with specific tissue/organs.
I have transcriptomic data from different tissues of a bird and I would like to know if some of the putative active metabolic pathways are out of the canonical set of reactions ever found in that tissue in other species.
I could compare tissue-specific transcriptomes across multiple species; but Im looking for databases/tools that have curated information about tissue metabolism. Maybe at the level of proteome or metabolome?
Essentially I would like to find out, for example, if some skin specific pathway have signal in liver or some detoxification reaction usually found in liver are localized also in the intestine.
I thank you in advice for your comments and suggestions,
Best regards,
Roberto
Hi,
If you have a list of upregulated genes eg. of your skin specific pathways, you can put the list into enrichR (https://amp.pharm.mssm.edu/Enrichr/), which gives you results from plethora of databases (KEGG pathways, tissue expression, GO terms etc.) enriched in your gene set for orientation.
Cheers, Vera
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