Two tablets aspirin per week leads to lower absorption of Vitamin C
Even in the market: BAYER ASPIRIN PLUS C
http://home.intekom.com/pharm/bayer/baspir-c.html
https://vitamins.vitanetonline.com/index.php/aspirin-affects-absorption-vitamin-c/
Dr. Fiona Godlee (Editor of The BMJ):
"I think we have to call it what it is. It is the corruption of the scientific process. ... Patients do get hurt. Drugs that shouldn't be available are available. Drugs with harms are used and patients are unaware of those harms. Devices that shouldn't be on the market are on the market. So yes, we do know that patients are harmed, and we know that the health systems are harmed as a result of poor science."
Source:
https://www.sott.net/article/317717-Fiona-Godlee-BMJ-editor-takes-on-corruption-in-science
Aspirin as drug interact with absorption of Vitamin C I.e. lower absorption of vitamin C
Unfortunately, much wronger combinations exist. For example iron + vitamin C is a very dangerous mixture.
"CIRCULATING FREE IRON IS LETHAL. Humans have two circulating iron binding proteins to soak up free iron to prevent it from generating toxic quantities of free radicals. These proteins are transferrin, a high affinity, low-capacity protein (2 atoms of iron per molecule of transferrin) for which there are receptors on the surface of every iron-requiring cell; and ferritin, a lower-affinity, high-capacity protein (maximum of 4500 atoms of iron per molecule of ferritin) for which there are receptors only on the surface of iron-storage cells such as RE (reticulo-endothelial) cells. Iron is trapped inside the ferritin protein shell as harmless Fe3. When there is a high serum level of reduced ascorbic acid, it drives through the pores of the ferritin protein shell to the inside surface, where it converts the Fe, to catalytic Fe2, which then leaks out of the pores of the ferritin protein shell and GENERATES BILLIONS OF RFEE RADICALS. In normal individuals, per milliliter of serum, there are approximately 300,000 molecules of transferrin per molecule of ferritin. Ferritin protein is an acute phase reactant that sharply rises in the presence of inflammation of any kind, whereas transferrin is a reverse acute phase reactant that falls in the presence of inflammation of any kind." (And produces oxalic acid!!)
Source:
Herbert V, Shaw S, Jayatilleke E:
Vitamin C-driven free radical generation from iron.
J Nutr. 1996 Apr; 126(4 Suppl): 1213S-20S.
https://www.ncbi.nlm.nih.gov/pubmed/8642459
http://prijatelji-zivotinja.hr/data/file_4524.pdf
Even in the market
One tablet of Sorbifer Durules contains 100 mg Fe (as dried ferrous sulphate) and 60 mg vitamin C.
https://www.ncbi.nlm.nih.gov/pubmed/15635885
https://www.ncbi.nlm.nih.gov/pubmed/12563623
Vitamins + minerals: Supradyn (Bayer, 13 vitamins + 9 minerals) (80 - 180 mg Vitamin C, 14 mg Fe, 2 mg Mn, 1 mg Cu - also incompatible with ascorbic acid ...) https://www.bayer.at/static/documents/produkte/gi/supradyn/SupradynActiveFilmtabl.pdf https://www.bayer.at/static/documents/produkte/gi/supradyn/SupradynForteTabl.pdf
etc. ...
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