Protein and biochemical secretions from small microbes must not go waste. Is this more efficient by orchestrated secretion of different biochemicals or quantized secretion via outer membrane vesicles like:

https://www.researchgate.net/publication/230793514_Eukaryotic_cell_intoxication_by_Gram-negative_pathogens_A_novel_bacterial_outermembrane-bound_nanovesicular_exocytosis_model_for_Type-III_secretion_system._Toxicology_International_vol._10_No._1_pages_1-9_year_2003?ev=prf_pub

Article Eukaryotic cell intoxication by Gram-negative pathogens: A n...

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