It it to difficult for diabetic patient to take regular insulin by parenteral route.
Kindly provide informaiton on source of new insulin delivery system
Hello Pravin,
A while ago, I've heard of administration of insuline using a nasal spray.
Actually, the idea of using the respiratory mucosae for aerosol administration of this hormone is not new, I've easily found a paper back to 1971 !
10.2337/diab.20.8.552
I haven't checked further, there may even be other previous papers.
A recent study showed mitigated results though.
10.2337/db10-1360
Several reviews have been published for alternative methods to injection.
For example : 10.1016/S1262-3636(06)72804-X
As I know, Insulin patch can also be useful for same purpose.
Another recent option: Stomach Patch Insulin Pump can also be useful to deliver insulin in regulated manner...
Dear sir,
Their are lots of insulin preperation available
• Glulisine -
rapid acting insulin analog from Sanofi-Aventis
approved for use with a regular syringe, in an insulin pump or the Opticlik Pen
Oral insulin:
Strategies to produce orally active insulin have included formulations with …
enteric coating
structural modifications
use of protease inhibitors.
Hexyl-insulin monoconjugate 2 (HIM2) was developed by covalently linking an amphiphilic oligomer to the free amino group of Lys-β 29 of insulin.
This structural modification makes the insulin resistant to enzymatic breakdown and thus facilitates absorption.
INSULIN PENS - SIMPLIFY INJECTIONS for those who have difficulty measuring insulin in a syringe.
INSULIN PUMPS - (primarily used for type 1 diabetes) - about the size of a pager - PROVIDES CONTINUOUS INFUSION OF INSULIN, allows for diabetes to be better controlled and more flexibility for scheduling meals and daily activities.
INHALED INSULIN - may be used in combination with a once-daily injection of a long-acting insulin to provide pre-meal coverage and as a supplement when the blood sugar is elevated.
I hope these data will help you better.
Thank you
Hello Pravin,
what is exactly the problem of insulin administration?
We have used an insulin pump ( Roche) for a 2,5 kg infant wich worked out without relevant problems. An other possible way might be a sucutanous port catheder as in the attached link www.childrensmn.org/Manuals/PFS/HomeCare/028428.pdf
kind regards
christian
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