More information is needed to be able to answer this question more precisely. There's the need to know the chromosome involved, and the inverted region of the chromosome. These information are requested in order to assess the impact of the inversion. For instance if the region is such that there's no possibility of position effect, there is little or no cause for alarm. Furthermore, it is also important to know whether the inversion polymorphism is somatic or germline. If it's somatic, there won't be any course for alarm because it won't be transmitted to an offspring. Even if it's a germline aberration, and the chromosomal region affected is intergenic, there won't be need for worry since inversion preserves genic balance. In short more detail information are needed for proper characterization of the aberration in order to give a more definite counselling advice.

@idowu. It's somatic and probably if the inversion is on recommendations region, will it effect the meiosis ( in gametogenesis?

"Hi. Which chromosome? where are the break points ? how much the lenght of inversion.

If the chromosomal break points are occured near or in an important gene, with Dominant mode of inheritance, depending on mandelian inheritance roles

50% of all of outcomes will be affected, if recceive, the wife must be cheked for the same gene.then define the probability of affected children for the next generation. normal karyotipe can not define the healthy situation of the genes.

if the lenght of inversion is too much, depend on miosis behavior of chromosomes, the inversion can not affect the borned children, and affected zygotes can not tolerate the big size deletions and duplications.

if the size of inversion is small, we must expect zygotes harboring some deletions or duplications for the mentioned area of the chromosome