After muscle or muscle-skeletal trauma, about how much time clinical analysis can be performed to detect blood myoglobin. What levels are considered positive, and what factors can cause a false-positive result in detection.
Myoglobin can be elevated with any form of injury to skeletal muscle. It is cleared rapidly and has a reduced clinical sensitivity after 12 hours.
It may depend on the kind, intensity and frequency of trauma, though.
Myoglobin may be toxic to the kidneys, and is mainly used as a surrogate indicator (but not diagnostic) of muscular lesion of many origins (it´s called "rhabdomyolysis). Some other factors can raise it.
It can be raised after moderate to strenouous exercise (specially anaerobic and exercised in very fast rythm) and blunt muscular trauma, among other causes, in an otherwise healthy individual.
The use of statins or other drugs can interfere (causing higher values) - and not necessarily meaning clinical disease, or prohibiting body-building. In that case, your values would have to be individually adjusted, though -- f you´re on statins and, say, would like to keep on an intense body-building exercise. Some body-builders experience enhanced levels on the start of the regimen, just to wear off gradually to "normal" levels.
That process might mean taking a "basal level" - like not using statins for a while, or using statins and without intense exercise for 2 days to a week - and then observing how it raises and lowers (make a curve), according to yohur enhanced activity level.
Ther result might mean an advice to change your drug, if you´re on an intense body building program, have very high Myoglobin levels and don´t want to stop. But also, the intensity of the effects of body building on Myoglobin may wear off, as you gradually change your body constitution to a "more massive" body build -- and then rise again, if you stop for a time (say, a month) and start over again.
It´s very individual, and it doesn´t mean necessarily a sustained pathologic condition. Neither can it be used as a surrogate marker for "body health or fittness".
Have a look at the links:
http://www.ideafit.com/fitness-library/exercise-overexertion
http://labtestsonline.org/understanding/analytes/myoglobin/tab/test/
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