I want to know whether it's possible for us to make the nanoparticles (chitosan) to get absorbed into blood escaping the digestive system.. Oral feeding is the method of nanoparticle administration.
Why you have chosen the oral administration, when you really need the NP in blood? Is any particular reason behind this? YOU can try do IV formulation straightaway ......
I think you discuss the Oral feeding as a new simple way to introduce the nanoparticle? If yes let us point out the available ways to do this.
Mr.Venkatachalam and prof.Tawfik thank you for your reply.
yes oral feeding is the method of option as i am trying to develop a food product out of these nanoparticles..
Ramya Srinivasa , pls.Do you have some ref. I can read about ? [email protected]
To maximise the absorption of NPs, You can try few of the strategies like 1. improving hydrophobic/lipophilic balance of your particles using surfactants, coating/making the NP with different pH labile polymer(i.e acid resistant) which will traverse throughout the intestine will ensure the complete absorption of NP into the blood.
Hi ....please read out this article, its cross references and citations ....you may get lot of clarifications regarding you work. https://www.uclouvain.be/cps/ucl/doc/farg/documents/desRieuxJCR2006.pdf
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