Hello! I need to snap freeze cancer pellets to submit for multiomics. Does anyone know of 15 mL conical tubes or Eppendorf/microcentrifuge tubes that can withstand liquid nitrogen and dry ice?
You could test a couple of different manufacturers' vials to see which ones cope with the stress of freezing. I experienced the opposite issue with heating polypropylene vials that had been gamma irradiated in the factory and found they melted at a lower than expected temperature. Try out a few vials and see if they crack or split when frozen (or the lids fail upon returning to room temperature). You may need to adjust sample volumes or pre-cool the sample before going into liquid nitrogen.