Central Nervous System

What is the effect of Inter-nodal distance on transmission speed in Myelinated Nerves?

In one of our biomedical project, we need to evaluate the effect of increasing inter-nodal distance (of the nodes of Ranvier) on the transmission speed of the action potential in Myelinated Nerves.

10 October 2014 5,160 1 View

Has a relationship between plasma and CNS levels of non-BDNF neurotrophins, NGF, and BDNF been established?

This study looked for a plasma marker for depression and treatment efficacy sertraline. Yet, what does this mean for pathophysiology of depression taking into account that, to my knowledge...

09 September 2014 4,260 2 View

What is currently the best method to measure muscle fatigue?

How does the nervous system fatigue impact muscular fatigue?

04 April 2014 5,849 5 View

What is the best way for quantifying aggregates in the fruit fly CNS?

Imaging technique to be followed, sample number for a good statistical estimate?

02 February 2014 2,746 1 View

Tissue-level thresholds for axonal damage of CNS tissue?

I am looking for someone that knows about tissue-level thresholds for axonal damage of CNS tissue? Low strain 1-2% and strain rate 0.1 1/s.

01 January 2014 259 1 View

Has any research been done about depicting dreams into images or video?

Dreams to images

12 December 2013 1,875 9 View

What is the function of astrocytes in neurogenesis?

Astrocyte is the building block of CNS and its activation has a beneficial role in maintenance of CNS. What is its function in the genesis of the neuron?

11 November 2013 7,188 2 View

What are the protocols in obtaining the markers of inflammation in adult drosophila CNS?

I need urgent assistance on protocols involving the following areas of Drosophila neurobiology: (a) assays of markers of inflammation in the CENTRAL NERVOUS SYSTEM of adult Drosophila, e.g...

10 October 2013 9,212 3 View

How can we explain the pathogenesis of Trypanosomes in the central nervous system?

This in relation to animal trypanosomosis?

09 September 2013 5,195 1 View

How can we explain the pathogenesis of Trypanosomes in the central nervous system?

This in relation to animal trypanosomosis?

02 September 2013 3,562 1 View

Does anyone know if there is a demonstration that cytokines could be acting as neurotransmitters in the CNS?

I know that there is a demonstration of increased intracellular calcium in astrocytes induced by TNF-a, but I couldn't find evidence showing that this could occur in neurons.

03 March 2013 4,999 7 View

How can I tell if the activated microglia I have in the human CNS are the good or bad guys?

I run fluorescent immunostaining on human CNS for Iba1. I found several activated cells and I need to know if they are "the good" or the "bad" microglia. Any suggestions?

03 March 2013 1,095 8 View

Does the mouse glioma cell line "GL261" or the rat glioma cell line "9L or 6C" express ROR1?

A large number of human CRC, breast cancer and NSCLC displayed strong surface ROR1. ROR1 is also expressed in the CNS. Which murine glioma cell lines express ROR1?

01 January 2013 9,888 0 View

In which disc surgery does redo and CSF leak occur?

I want to do a retrosepective study at northwest general hospital for CSF leak as a complication of disc surgery as well as redo disc surgery incidence.

11 November 2012 7,534 3 View

Can anyone recommend a small molecule ligand or aptamer to specifically target nanoparticles towards astrocytes?

I'm looking to have nucleic acid nanoparticles taken up by astrocytes in a multi-cellular CNS environment. Does anyone know of a small molecule (e.g. a glutamate) or aptamer that has been...

11 November 2012 7,062 3 View

Does anybody know any automated method to quantify microglia morphology?

I know this method published in PLoS ONE but do not whether I will be able to use it as I do not have matlab. I will try to use ImageJ or FIJI... Kozlowski C, Weimer RM (2012) An Automated Method...

09 September 2012 4,221 8 View

Hi dear professor. I want to know about these proteins and are thier proteins or peptides related to disease such as multiple sclerosis?

what kind of proteins, those produced into the CNS or those secreted by muscle? and do you use any intervention for delivering them to CNS? what are the application of them into the brain?

01 January 1970 251 2 View

I realize this is a project that is underway; can I be of assistance in any way?

It is my read of the research that a chronic progressive decrease in the availability of metabolizable energy resources in the CNS is a primary cause of several neuropathologies, including...

01 January 1970 8,705 1 View

What are the benefits for the central nervous system ?

I know a toddler (11 months) who is suffering of mucopolysaccharidosis type II. Could you help me to find some research about ex vivo GT ?

01 January 1970 202 0 View

Does the pain for the survival of the human have any meaning?

. Does the pain for the survival of the human have any meaning? . The cellular and tissue thermal or chemical lesion causes a sensation and avoidance reflex, to avoid further damage to the...

01 January 1970 2,036 5 View

Can neural cell be cancerous?

can neural cell either CNS or PNS be cancerous?

01 January 1970 1,463 6 View

Does anybody know if Gaspard's time-reversal entropy has ever been correlated with biological structures?

To make a theoretical example:  http://arturotozzi.webnode.it/products/a-link-between-time-reversal-asymmetry-and-fainting-of-memories-/

01 January 1970 7,235 3 View

No title

01 January 1970 9,461 0 View

Are there how many types of hydrocephalus?

We have a cases of CNS sarcoidosis with flow obstruction of spinal flluid at scull base.But this is the case of secondary hydrocephalus, Are there　essential hydrocepharus?

01 January 1970 4,176 1 View