8 Questions 13 Answers 0 Followers
Questions related from Tony Tiller
I am determining drug recovery of liposomes, before calculation of encapsulation efficiency, against a calibration curve using UVvis spec. I would like some advice on whether this is a correct way...
10 October 2019 5,060 4 View
As I understand it this involves esterification and saponification of ester bonds and involves a pH gradient to encapsulate liposomes. Is this correct? Can someone provide an explanation of what...
05 May 2019 7,299 5 View
When dealing with molar ratios for liposomal formulation, I have a particular mg of sodium ascorbate and phopshatidylcholine per 5ml as my reference (roughly 1g SA and 500mg PC per 5ml) I want to...
04 April 2019 8,811 1 View
I need clarification as to whether my calculation is correct: One paper found 41.3nmol/550uL (well volume) liposomal curcumin resulted in LD50 One the other hand 46.37ug/mL of niosomal curcumin...
03 March 2019 7,176 4 View
Can someone provide a simple explanation of calculating molar ratios to weights. For example, I have a molar ratio of Phosphatidylcholine, Sterol, and glycerol at a Molar ratio of 2:1:0.1. I know...
03 March 2019 4,692 2 View
Given that most natural phopsholipids (PS, PC etc) are at their fluid phase (predominant fatty acids 18:2 and 18:3) at room temp, and antioxidants and vitamins are heat labile. If one were to...
02 February 2019 9,284 5 View
If comparing formulations of curcumin reported in the literature, which are also available commercially, by their Cmax values, if they have all used different doses, is it scientifically...
12 December 2018 1,068 5 View
It's a comparison of liposomal vitamin C to non-liposomal vitamin C. There were 21 geometric mean data points taken from each test group. I have the SD for each data point, there is some...
11 November 2018 8,543 4 View
