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Questions related from Thomas W Stief
APTT/PT measure thrombin activity in blunted clotting seconds, ultra-specific thrombin generation tests are at least 1000fold more sensitive and would reflect the real hemostasis state of the...
12 November 2015 8,539 14 View
Dichloroacetate (like chloramines) might be a generator of singlet oxygen.
20 April 2015 3,081 0 View
Integrated blood ROS generation is too time consuming, preferable could be one time point in the begin of blood ROS generation.
19 February 2015 8,649 4 View
Altered Matrix activates the contact Phase of coagulation, then Infusion of prothrombotic Fibrinogen may be risky.
18 December 2014 4,490 4 View
Severe Sepsis is often caused by germs that release LPS or ß-glucans, that are toxic for blood monocytes. Monocyte fragments generate systemically circulating thrombin.
21 October 2014 3,599 4 View
Just before starting the experiment, should I check if the singlet oxygen release power of the oxidants is still ok? Oxidation: 4 mol/L KI.
10 October 2014 5,288 3 View
Neutrophils generate large amounts of singlet oxygen (via NADPH-oxidase/myeloperoxidase mediated generation of chloramines). Physiologic activation of neutrophils results in an anti-thrombotic...
10 October 2014 3,500 3 View
Plasmin. Blood should be drawn into Arginine/EDTA, 0.1 U/ml is the target.
11 September 2014 1,876 4 View
Limulus inhibitors in human plasma have to be eliminated.
14 July 2014 8,228 7 View