Thomas W Stief

6 Questions 30 Answers 0 Followers

Questions related from Thomas W Stief

Is there any advantage of old APTT or PT to new ultra-specific thrombin generation tests?

APTT/PT measure thrombin activity in blunted clotting seconds, ultra-specific thrombin generation tests are at least 1000fold more sensitive and would reflect the real hemostasis state of the...

12 November 2015 8,530 14 View

Can dilutional coagulopathy increase thrombin generation ?

Altered Matrix activates the contact Phase of coagulation, then Infusion of prothrombotic Fibrinogen may be risky.

18 December 2014 4,481 4 View

Can the power of singlet oxygen releasers be hampered by preanalytic redox reactions?

Just before starting the experiment, should I check if the singlet oxygen release power of the oxidants is still ok? Oxidation: 4 mol/L KI.

10 October 2014 5,275 3 View

Is singlet oxygen the mediator of ozone-induced inactivation of F13?

Neutrophils generate large amounts of singlet oxygen (via NADPH-oxidase/myeloperoxidase mediated generation of chloramines). Physiologic activation of neutrophils results in an anti-thrombotic...

10 October 2014 3,486 3 View

What is the best biomarker to monitor the sufficiency of fibrinolytic therapy ?

Plasmin. Blood should be drawn into Arginine/EDTA, 0.1 U/ml is the target.

11 September 2014 1,863 4 View

What is the best method to quantify endotoxin in human blood?

Limulus inhibitors in human plasma have to be eliminated.

14 July 2014 8,217 7 View