Jack Chang

5 Questions 7 Answers 0 Followers

Questions related from Jack Chang

Would you represent a Glucose Tolerance Test with glucose levels as percent of time 0?

Hi, I have performed a glucose tolerance test (GTT) on mutant vs WT mice and I have no statistical difference in glucose levels (mg/dL) during the test between the mutant and WT mice, and no...

11 November 2017 5,711 3 View

Do you know why Glucose Tolerance Test is often performed in mice fasted 6h while Pyruvate Tolerance Test is mostly done on mice fasted overnight?

Hi, From the litterature I found that Glucose Tolerance Test is often performed on mice fasted 6h, while the fasting period for a Pyruvate Tolerance Test is overnight in most of the articles. Do...

11 November 2017 5,921 2 View

Can I combine data of different glucose tolerance tests to have better statitics?

Hi, I performed several glucose tolerance tests (GTT) to assess glucose tolerance in mutant mice compared to WT mice. Each test was done on 5-6 mutant mice and 5-6 WT mice at the same time. All...

11 November 2017 863 4 View

For what reason(s) do auto-antibodies anti-insulin could be elevated in the blood of mice?

Hi, I have a mutant mouse model in which there are increased auto-antibodies against insulin in the blood. Does someone know why these autoantibodies could be elevated in mouse blood? Thank you.

10 October 2017 7,476 0 View

How a change in gluconeogenesis genes expression levels can affect the gluconeogenesis pathway flux and glucose production?

Hi, I have a decrease of 1/3 to 1/2 in the gene expression of gluconeogenesis enzymes (Glucose-6-phosphatase, Fructose-1,6-bisphosphatase, Phosphoenolpyruvate carboxykinase and Pyruvate...

07 July 2017 6,009 6 View