Israel Ebhohimen

9 Questions 26 Answers 0 Followers

Questions related from Israel Ebhohimen

There is almost a general consensus that lipids are more susceptible to oxidation than proteins and DNA. Is this scientifically correct?

Is this consensus based on the fact that lipid oxidation is more easily determined? could it be their membrane composition? are there reports on oxidation of other biomolecules in subcellular...

31 May 2021 5,845 1 View

How do we balance the argument on the effect of hydroxychloroquine in Covid-19 prophylaxis and treatment?

Hydroxyl-chloroquine has been listed as a potential drug in the management of Covid-19. The effect of this drug in Covid-19 prophylaxis and management is trending on social media. The Doctors...

30 July 2020 2,761 4 View

The challenge with research on medicinal plants in Africa is mainly based on working with crude extracts. Do you have active components in mind?

Because crude extracts always vary in composition, similar preparations produce different biological responses. Is this project focussing on the identification and determination of the active...

25 March 2020 4,566 3 View

Can anyone help with a detailed assay procedure for the spectrophotometric measurement of protein carbonyls in tissues?

Protein carbonyls are important compounds to measure progression of oxidative stress in tissues. Available articles online do not have details about how to do final estimation/calculation of the...

07 February 2020 3,109 8 View

Is the transfer of acetyl-CoA to the acyl group in the mitochodria different from the reaction in the cytosol?

Pyrophosphate cleavage of ATP and further degradation of PPi accompany the formation of fatty acyl-CoA in the cytosol during beta-oxidation of fatty acids. When transported into the mitochodria as...

21 October 2019 4,889 0 View

Is the transfer of acetyl-CoA to the acyl group in the mitochodria different from the reaction in the cytosol?

Pyrophosphate cleavage of ATP and further degradation of PPi accompany the formation of fatty acyl-CoA in the cytosol during beta-oxidation of fatty acids. When transported into the mitochodria as...

16 October 2019 5,746 0 View

How do I calculate protein carbonyls using the DNPH method?

I am gathering articles that will be useful for my intended study; 'protein oxidation in freeze-stored meat tissues'. I have seen several articles that describe the procedure in detail but no...

26 September 2019 8,770 3 View

What does it mean when the concentration of secondary peroxidation product decrease after extended periods?

I set up an experiment to determine the inhibitory capacity of an antioxidant on lipid peroxidation. The outcome was positive as MDA concentration increased faster in the control group. However,...

21 July 2019 3,701 4 View

Reverse Pharmacology. key feature in 21st century drug disovery processes?

It is a whole lot much easier to find a solution when the problem is well understood. Available in silico tools afford scientists today this unique approach of first understanding the biochemistry...

01 January 1970 6,011 3 View