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Questions related from Houra Naraghi
I am using a peptide and have faced challenges in preparing a transparent peptide solution. My goal is to prepare a peptide solution in MES buffer and then use the solution to immobilize the...
21 June 2024 8,490 5 View
Exploring the release rate of paclitaxel from a mesoporous silica nanoparticle, prior studies have employed various release mediums, such as PBS buffer, or PBS supplemented with Tween or SDS at...
08 March 2024 4,505 2 View
I have a peptide dissolved in DMSO and MES buffer, and I aim to determine its absorbance using UV-Vis spectroscopy. However, I'm encountering issues with obtaining meaningful results at 220 nm,...
30 November 2023 258 3 View
I have an acidic peptide with 12aa (containing 5 hydrophobic amino acids), disulfide bridge, Methionine, and amidation at the C-terminal. I have tried dissolving using acetonitrile, NH4HCO3 0.1 M,...
10 July 2023 2,976 6 View
I want to design a drug delivery system using peptides as targeting ligands which are supposed to interact with cell surface receptors. Has anyone experienced a similar experiment to help with the...
16 April 2023 6,862 0 View
08 February 2023 2,355 0 View
I synthesized a short hydrophobic peptide and confirmed its synthesis using MALDI_TOF analysis for the crude sample. Before purifying using a semi-prep column the sample was injected into the...
19 January 2023 1,074 6 View
Dear all I want to lable mesoporous silica nanoparticles with the 5(6)-Carboxyfluorescein (FAM) dye. Do you have any suggestions about the following: - What is the functional group of FAM? Is...
31 August 2021 4,906 4 View
How can I find peptide properties like its surface area, volume, anchoring amino acids for binding,? Is there any data bank or online calculator for this purpose?
25 March 2021 7,685 6 View
