Giulia Fulias

11 Questions 26 Answers 0 Followers

Questions related from Giulia Fulias

What are the disadvantages of nanoparticles in drug delivery?

Please give reference if possible.

26 June 2016 3,438 12 View

Nanoparticles have hydrophilic polymer (surfactant) .When NPs are centrifuged for separation, does not it cause the release of drug entrapped in PVA?

Every nanoparticles formulation has a hydrophilic polymer as a surfactant such as PVA. When nanoparticles are centrifuged for separation, does not it cause the release of drug which is entrapped...

15 May 2016 2,618 14 View

To analyze the size of Ethyl cellulose and HPMC nanoparticles by zetasizer, how to redisperse them and in which medium these should be redispersed?

Also tell how much volume of liquid should be used to redisperese them. How much amount of sample should be taken to redispere in liquid. Kindly give a detailed reply

04 May 2016 4,884 8 View

Hi, How to find drug release when entrapment efficiency is low?

i am preparing nanoparticles, drug is hydrophilic and entrapment efficiency is very low. If i find the drug release by dividing with the total drug taken its giving very low drug release so is it...

24 March 2016 6,355 12 View

My drug is hyrophilic, drug content is 0.9 % and entrapment efficiency is 8 %. Now how to calculate the % age drug release for nanoparticles?

Waiting for reply.

23 February 2016 9,454 3 View

Hi, I have to perform dissolution on USP Dissolution Apparatus 2, so I can add nanoparticles in basket?

Thank you.

18 February 2016 7,755 3 View

I want to know about evaporation of some volume of aqueous phase along with the organic phase?

I have 60 ml aqueous phase and 10 ml organic phase for nanoparticles while evaporating organic phase if I evaporate 40 ml of water too at rotary evaporator, is it right?

22 January 2016 4,974 4 View

What can be the appropriate amount of tween 80 in nanoprecipitation method if polyme is 40 mg, organic phase is 10 ml and aqueous phase is 20 ml?

01 January 2016 2,676 4 View

I have to prepare nanoparticles of a freely soluble drug, can I keep external phase as water? I suspect that drug may not dissolve in aqueous phase?

I am using emulsion solvent evaporation method.

15 December 2015 7,628 2 View

Can we give a suspension of Eudragit nanoparticles by nasal spray?

If I prepare Eudragit nanoparticles and later convert it to suspension and use it as nasal spray, would it be ok? Remember drug is neither for respiratory tract, nor it has to target brain. I have...

05 November 2015 3,087 2 View

Can we give a suspension of Eudragit nanoparticles by nasal spray?

If I prepare Eudragit nanoparticles and later convert it to suspension and use it as nasal spray, would it be ok? Remember drug is neither for respiratory tract, or it has to target brain. I have...

04 November 2015 6,296 3 View