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Questions related from Anindita Sarkar
What is the effect of diluent in nitrosamine recovery? Candesartan Cilexitil is insoluble in water but we are getting good recovery in water and not in methanol for certain nitrosamines (NDIPA,...
05 March 2023 288 0 View
04 March 2023 2,018 1 View
I am trying to develop dissolution method of Liposomal Doxorubicin. Can anyone suggest a method for the same?
08 October 2021 1,934 5 View
Is there any method which can differentiate HPC and HPMC?
18 March 2020 8,128 2 View
I am looking for a method for estimation of EDTA (ppm level) without formation of chelation. Please share a method of the same.
13 November 2018 2,936 3 View
We are facing issue in vitamin B12 assay as we cannot correlate by mass balance in force degradation. We are having HPLC with UV Detector method.
19 September 2018 7,047 8 View
Can anyone suggest a method to identify grade of HPMC (whether 2910 or 2906 or 2208) in suspension formulation having HPMC content 0.5%
17 September 2018 3,534 3 View
I am looking for a method of estimation of propylene glycol alginate in pharmaceutical solid oral formulation.
13 December 2017 5,630 2 View
How to precipitate sodium bisulfate from a solution?
06 November 2017 5,295 2 View
We are facing a problem in detecting polysorbate 80 in aqueous suspension as it is not detecting in HPLC. If we are spiking PS 80 in the vehicle, it is observed that the area is very less compared...
04 November 2017 847 0 View
We have followed a literature method for NaHSO3 and NaHSO4 Detection by HPLC (Literature attached) in suspension formulation. Though we are receiving the peak of NaHSO3, unfortunately no peak of...
02 November 2017 9,227 2 View
An API is formulated with PEG 3350, Polysorbate 80, NaCl, Methyl paraben. While heating small batch in water bath at 120 C , no color change was observed, but while heating in an autoclave of...
20 September 2014 3,318 9 View
An organic compound having two forms, I and II. In DSC study we found form-II is slowly transforming to form-I (about 5% in 40 days). But XRD study is not showing any transformation. Why is PXRD...
17 February 2014 4,546 12 View
I am looking for a clue of the following issue: We are getting a good recovery of the following nitrosamine in methanol and poor recovery in Candesartan Cilexitil: NDIPA, NDPA, NMPA, NDBA As...
01 January 1970 5,217 0 View
