I have only used the bispectral index monitor on adult trauma and neurotrauma patients with the intent to monitor the level of sedation while intubated and receiving continuous IV drips of propofol, ativan, versed, and/or ketamine. I found that the bespectral index monitor was useful in this setting, but monitoring for subclinical seizure activity or for burst suppression we found that the continuous EEG monitoring was most useful.

An interesting study could include the pairing of both monitoring systems simultaneously and then statstically analyze the difference using the Bland-Altman plots.

Dear Wayne ,thanks for your advice

Please see this article

Can BIS monitoring be used to assess the depth of propofol

anesthesia in the treatment of refractory status epilepticus?

*Tadeusz Musialowicz, yEsa Mervaala, zReetta Ka¨lvia¨inen, *Ari Uusaro,

Epilepsia, 51(8):1580–1586, 2010

doi: 10.1111/j.1528-1167.2009.02514.x

Thank you for the reference

Actually we use continuous EEG and BIS for monitoring Refractory SE and we found ,like your work ,a BIS less than 30 had a good correlation with a Burst suppresion index in children with RSE

Raul

He have published the use of the bilateral BIS monitoring in patients with nonconvulsive status epilepticus and even in a patient with myoclonic status epilepticus secondary to cefepime, in order to evaluate the sedation.

Dr Fernandez gracias por sus reprints