How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

Binary Logistic Generalized Linear Mixed model in SPSS. Is it doable?

I want to analyses the proportion of swimming sperm of three species of fish in two salinities. To analyse the proportion of swimming sperm in a Generalized Linear Model, I would use a Binary...

03 March 2021 2,297 3 View

Looking for Materials with high thermal expansion coefficient and high temperature resistance?

03 March 2021 8,272 1 View

Guidelines for survey (question type) analysis?

Hi. Please tell me what guidelines should i need to follow for questionaries' type research work in India. It is not hospital based work, we are conduction basic institutional based qualitative...

03 March 2021 2,037 3 View

What are the values needed for gabor filter's parameter for cifar10 data?

Hi, I implemented a code to gabor filter cifar10 data but the images after being filtered and stacked are not clear like the original images. I think the problem is in the way I am using the...

03 March 2021 6,317 1 View

Can we block unwanted images during the x-ray prediction?

i am try to classify the x-ray images. During classification , can i block unwanted images (except x-ray image).

03 March 2021 7,100 1 View

No title

03 March 2021 5,360 2 View

What techniques can I use to determine the miscibility of polymer blends?

The term miscibility refers to the single-phase state in thermodynamics. I do not mean the compatibility of different components. To determine the miscibility I know several techniques such as...

03 March 2021 4,107 4 View

Sample dilution for quantitative analysis using ELISA?

If the detection range is in ng/ml but the reference range is in ug/ml for a molecule or protein in serum or plasma .how to dilute and what is the initial volume to be taken for quantitative analysis

02 March 2021 7,670 3 View

The procedure compute?

02 March 2021 5,204 3 View

What is the significance of (isolated) high titers of IgG anti GD1a antibodies in an older patient with polyneuropathy?

Remote history of Campylobacter infection with reactive arthritis, and Spitz nevus (UMP). Arthropod exposure in Zika/ChikV endemic area prior to emergence of length dependent, sensory PN with...

18 February 2021 8,719 1 View

mRNA vaccines against Covid-19 may worsen cronic autoimmune disease?

Example: if a patient suffers of a 15 years psoriatic arthritis and gets Leflunomide (20 mg/ or 40 mg per day) and methilpredisolone (4mg per day). Then, his turn arrives to be vaccinated against...

11 January 2021 7,788 11 View

What about new vaccines for Covid-19 and autoimmune diseases ?

Many people, who are going to be vaccinated soon, suffer a variety of autoimmune diseases (i.e. reumatoid arthritis or psoriatic arthritis and many others). In particular, some of them are...

05 January 2021 6,069 3 View

What is the difference Knee joint Cryo section vs Paraffin section?

I have a tissue that causes arthritis with MIA. Usually everyone uses Cryo or Paraffin section for knee joint. What's the difference?

23 December 2019 8,103 5 View

How effective is warm water therapy in weight loss, diabetes, arthritis, etc.?

Warm water therapy (actually luke warm water mixed with/without lemon juice, salt etc) is becoming very popular among health-maniac netizens especially aiming to weight loss and to cure/manage...

15 September 2019 2,983 17 View

Why cell lines are not prefered for rheumatoid arthritis studies?

29 August 2019 7,973 3 View

Why cell lines are not prefered for rheumatoid arthritis studies?

07 August 2019 1,263 4 View

Are there any biomarker to find the proper treatment for patients affected by psoriatic arthritis?

Cancer research has developed precise biomarkers to use a proper cure for different kind of cancers. Why there is no proper biomarker to find the precise treatment in autoimmune desease, such as...

25 July 2019 9,710 4 View

Did anyone knows from where I can get the pharmacological activity for my compounds for rheumatoid arthritis?

I am a researcher in medicinal chemistry wanted to work on rheumatoid arthritis. I want to know from where (preferably in India) I can get the pharmacological activity of my compounds??? It's very...

21 January 2019 2,094 8 View

Does somebody know that the expression of STAT5 in rheumatoid arthritis synovial fibroblasts (RASFs)?

Does somebody know that the expression of STAT5 in rheumatoid arthritis synovial fibroblasts (RASFs)? Although some report indicated that the expression of STAT5 in RASFs, we can not detect any...

18 December 2018 4,687 2 View