IL-6 and TNFa measurements in RA patients. What anticoagulants (heparin, citrate and EDTA) will not interfere with the levels of (IL-6 & TNFa)?

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Malcolm Nobre

Hello Hiwa K. Saaed

The investigators in the paper attached investigated the use of various blood collection tubes namely, sodium heparin, sodium citrate and EDTA. They concluded that sodium heparin plasma showed the most constant recovery of all cytokines tested and therefore is the preferred anticoagulant. Please refer to the article attached for more information.

Article Prerequisites for cytokine measurements in clinical trials w...

Best.

Hiwa K. Saaed

thank you Malcolm Nobre for your answer and attached article,