How to convert Terapeutic Human Doses to Cell Experimentation Doses?

"Toxicological evaluations revealed that Cur is found to be pharmacologically safe, even up to 12 g per day, as reported by several animal studies and in phase-I clinical trials Similarly,...

07 December 2020 3,012 1 View

Is it possible to get genomic context data on bulk of accessions?

I'm trying to build local gene synteny to identify homologs between different species. To do that, I've been accessing each individual gene of interest, going into gene view in NCBI and...

04 November 2020 9,038 2 View

Transmembrane Protein 3-D Coordinate File Preparation Question?

Hello I hope you are all doing well.:) Several transmembrane Pannexin1 3-D coordinate files have been submitted to the PDB, however, I believe all are missing coordinates in some of the Pannexin1...

11 August 2020 4,875 3 View

What are the best metrics for evaluating the quality of non-spherical clusters?

Hi. I'm dealing with clustering of data were the resulting clusters are, in general, non-spherical. Some of them are not convex. What are the best internal metrics for evaluating these kind of...

27 March 2020 5,076 2 View

How can I separate hematite from bornite in a powder?

17 March 2020 570 3 View

How can I access the total number of integration points present in my model using a vumat in Abaqus ?

Hello, I'm using a vumat in Abaqus and i'm storing data associated to each Integration Point present in my model. For the time being, I scale my array to a given large size, say M(10000). I...

08 January 2020 9,622 3 View

I have tried to clone dcas9 into pET22b vector for the past 1month now. And I do'nt always have any colonies. Anyone cloned dcas9 into pET vectors?

I always have pure insert and vector DNA in the region of 1.7-2.0. I use restriction enzymes sall HF and xhol and perform ligation overnight for 16hrs and then do transformation in 10 beta...

30 September 2019 7,178 2 View

Please, has anyone worked on sgRNA labelling? I am finding it difficult to get protocols to label with alexa dye and Qds.?

How can I label single guided RNA (sgRNA) with Alexa 488 dye and quantum dots (QDs)? I will appreciate any paper recommended or detailed protocols.

30 September 2019 6,873 1 View

How do I stop TEM samples being destroyed under electron beam?

The samples that I make for TEM contain cells. I need them to be 70-90nm (no higher) to be able to see them clearly and do EDX as well. However, They begin to rip and flex under the beam even at...

19 August 2019 2,339 1 View

Correct statistical analysis for intervention study pre and post test?

I have ran a study comparing the Daily Mile and HIIT in children to see which is best for improving cardiovascular endurance (Beep test) and anaerobic power (20m sprint). Scores on both test...

29 April 2019 7,457 2 View

Is there a validated survey for organizational team and individual performance?

I am working on a Capstone Project about trust and increasing performance (both individual and team) and need a validated survey to conduct my quantitative analysis. Does anyone know of a...

11 February 2021 3,567 3 View

What is the impact of learning organisation on innovation?

the impact of learning organisation in institutions of higher learning

09 February 2021 1,472 8 View

Student writing his own Learning Outcomes - is this the way forward?

'Students just dont want to study; they are here to waste time!' I have heard this phrase many times; so are the students solely to be blamed? We will find many students who just dont seem to...

04 February 2021 8,546 22 View

Is there anyone who have been working with factors concerning learning powers in different organisations?

I'm currently working on a masterproject and I'm exploring ceveral research question on the abilitiy to change, learn and adapt. The covid-19 has lead to a massive use of digtal homeoffice and low...

02 February 2021 7,175 4 View

(ORGANISATIONAL FACTORS ) request for study instrument?

i am currently conducting a study to assess bullying behaviors on student nurses during clinical placement . My objective is to explore organisational factors that influence bullying behaviours at...

25 January 2021 8,676 1 View

Can you suggest literature studying the conditions information and evidence can influence manager decisions in social impact sectors?

I am working on improving the use of digital innovations at scale globally. Most of the innovations I work with provide relevant knowledge on improving the performance of projects, programs, and...

16 January 2021 1,120 5 View

Any recommendation to calculate time to dominant design emergence?

Any recommendation to calculate time to dominant design emergence?

01 January 2021 3,809 5 View

Are drones following the e-Auto industry technological trajectory or are they following its own?

* Are drones following the e-Auto industry technological trajectory or it is following its own? * Will drones diffuse faster than electrical vehicles? * Will it depend on the application?, What...

29 December 2020 7,379 3 View

What is your opinion that the best ways to increase the efficiency of public authorities?

On the latest innovative methods of effective organization of public authorities or effective mechanisms in practice

29 December 2020 6,413 2 View

How best can Agricultural Innovation be structured to ensure adequate uptake and farmers adoption?

Technology adoption rates amongst small-scale farmers in the Global South (e.g. Africa) remain low, even when scientific evidence shows that a particular technology is beneficial.

28 December 2020 4,786 23 View