Dear colleagues,
I would like to know which approved or in current trials chemotherapy drugs (or formulation) might reach the highest concentration in lymphnodes after intravenous injection. Thank you for your time.
Andrea Guerini
Dear Andrea Guerini,
the references to these papers may give you an idea or you can discuss with the authors to these papers here on RG:
Article [Successfully resected stage IIIA non-small cell lung cancer...
Article Short course chemotherapy for lymphnode tuberculosis
Article Advanced Gastric Cancer with Liver and Lymph Node Metastases...
Conference Paper A phase II study of systemic chemotherapy with docetaxel, ci...
Article A case of advanced gastric cancer successfully treated with ...
If you google this you find a lot of smart guys explaining you how to download 1 year of citations of 1 single paper of yours (or anyone else). I mean 1 year of ALL my papers. or ... ALL years or...
01 March 2021 1,121 9 View
A few scientific journals have started implementing a "publish, then review" model of publishing. It is explained well in this article: Implementing a "publish, then review" model of...
13 January 2021 5,449 2 View
I'm far from being a Freud expert, but, my feeling is the 1950 translation by J. Strachey is in many ways outdated, when not misleading (starting form the very title of the essay, the awful choice...
10 December 2020 7,005 2 View
I am hoping to determine the mass per unit area (as per DIN 50938) of a black oxide coating. I use water to achieve the required 1mol/l hydrochloric acidic solution, but a fellow lab had used...
06 December 2020 4,806 1 View
Hello, I plan to perform a linear mixed model analysis to look at change in cognitive function over 5 follow up waves. I am interested in looking at how this change is influenced by dietary and...
27 November 2020 5,087 3 View
Elsevier announced that Mendeley profiles will be discontinued from December. There is a study (Mendeley readership counts: An investigation of temporal and... ) that confirms the value of...
01 November 2020 4,832 4 View
Hello everyone, I need to assess whether a MCMC chain (implemented in BayPass 2.2) has reached convergence and, as far as I know, in order to check it, I must look at the posterior distribution of...
27 October 2020 6,170 3 View
Dear all, I am looking for reliable antibodies for the adrenergic receptors alpha1D and alpha2A, to use in Western Blotting on human skeletal muscle tissue. Anyone with experience with good...
25 October 2020 9,421 2 View
What advice would you give to a young researcher who has to develop his/her ability to produce collaborative scientific work?
22 October 2020 5,934 8 View
I was reading the paper "Analysis of Temporal Noise in CMOS Photodiode Active Pixel Sensor" but I am a bit puzzled about noise calculation during integration. In particular, can someone explain...
15 October 2020 9,597 3 View
I looking for ferro calcium production process
03 March 2021 1,755 4 View
Hello, I am running a sandwich-type ELISA where I am trying to inhibit a protein-protein interaction using small molecules. For each experiment, I determine my Z' (Z-prime) to determine the...
23 February 2021 7,429 1 View
I have used Picral etchant (4.2 g Picric acid, 10 mL Acetic acid, 70 mL Ethanol, 10 mL distilled water) but it didn't work. Is there any alternative?
21 February 2021 2,558 5 View
I've just downloaded free trial version of LISREL 10.3 but I got stuck with importing .sav (IBM SPSS 25.) file. I mainly followed the steps of this video...
15 February 2021 752 2 View
I want to conduct a proliferation assay to test a chemotherapy combination on a cancer cell line. At first, I thought about the MTT assay. But now, all sources are saying that these do not measure...
14 February 2021 3,142 7 View
I am interested in using TLC to detect non-linear xylooligosaccharides. What would be the best visualisation solvent? Would aniline phthalate solution be suitable? I have also seen people...
02 February 2021 7,748 3 View
Number of methods are available to screen phytochemicals through extract prepared in different solvents including aqueous and organic. Is there any method/ published work related to phytochemical...
01 February 2021 7,348 4 View
01 February 2021 1,825 1 View
Dear researchers, Anticancer peptides(ACPs) with cell-penetrating properties can enter to cytoplasmic space of cancer cells and induce cell death. but, I could not find the database that...
29 January 2021 707 3 View
I'm in need of a reference or a method to come up with a protocol that allows one to get the protein-adjusted EC50 for an antiviral drug in presence of human serum albumin and acid glycoprotein.
27 January 2021 1,402 1 View