So sorry to hear about your tragic loss. Leukemia is essentially a systemic disease which means that cancer cells are spread throughout the body with blood stream. Chemotherapy works by attacking these cancer cells throughout the body and killing them. However, even in leukemia which is a chemosensitive cancer, a single dose of chemotherapy cannot kill all cancer cells as some cells may be relatively chemo resistant due to their cell cycle phase or because they are in a sanctuary site in the body(e.g. brain, testes) where chemotherapy penetration is not very good. We overcome these problems by giving repeated courses of chemotherapy over a period of time and also targeting sanctuary sites by intrathecal chemotherapy for brain and in some leukemias with cranial or testicular radiation. With each repetition of chemo exposure, there is a gradual decline in cancer cell population, until, hopefully every single cell is eradicated, leading to a cure. However, sometimes just a small amount of cells may develop resistance to chemotherapy and survive throughout the treatment course. These cells may be so small in number that they may not be detected by scans, blood tests or even bone marrow examination. However, they may regrow after a period of time and result in relapse of disease months or years later.
Hope this explanation allows you to make some sense of your tragic loss.
Thanks so much Dr Ather for your usful information. Besides that I was checking him monthly. Blood test and bone marow infestation. And he was gate 6mp tablet dose and petscan test. And his treatment was in india with good doctor. But I advice the doctor to not stopped the chemotherapy dose and must gate it for long time for example 5 years with cytoprin .but not agree .
For some people with acute lymphocytic leukemia (ALL), treatment may get rid of the cancer. Completing treatment can be both stressful and exciting. You may be relieved to finish treatment, but find it hard not to worry about the leukemia coming back. (When cancer comes back after treatment, it is called recurrence.) This is a very common concern in people who have had cancer.
It may take a while before your fears lessen. But it may help to know that many cancer survivors have learned to live with this uncertainty and are living full lives. See Understanding Recurrence, for more detailed information on this.
For some people, the leukemia may not go away completely. These people may get regular treatments with chemotherapy, radiation therapy, or other therapies to help keep the leukemia in check for as long as possible. Learning to live with cancer that does not go away can be difficult and very stressful. It has its own type of uncertainty. See Managing Cancer as a Chronic Illness for more about this.