Hi, everyone. I am doing CO2 reduction experiments and I wanted to use NMR to detect the liquid products formed. My media is organic (CH3CN). I have seen some similar works by Prof. Kubiak, et al. that use 1H-NMR to detect the liquid products (particularly, formic acid) in CD3CN but the NMR sample requires the addition of Verkade's base. I am not so familiar with this compound. Does anyone know why (1) the peak of formic acid is not visible (supposedly around 8.02 ppm) if you do not add this base, and (2) what happens between the base and formic acid that causes a peak at 8.50 ppm to occur? Thank you so much!
Verkade base is one of the strongest base; after protonation, it forms a conjugate acid with pKa value of ~33. That means it can deprotonate even a weakest acid and hence the signal disappears. This includes for your both the questions 1 and 2. Conjugate acid is = [HP......]+ [pKa = 33]
Best
Balakrishna
- Badges
- Science topic
- Similar topics
- Engineering
- Chemical Engineering