According to the european pharmacopoeia, the following identification method of paracetamol was defined:
" To 0.1 g add 1 ml of hydrochloric acid R, heat to boiling
for 3 min, add 1 ml of water R and cool in an icebath.No
precipitate is formed. Add 0.05 ml of a 4.9 g/l solution of
potassium dichromate R. A violet colour develops which
does not change to red."
And why do they mention that it may not change to red?
Thank you for your answer!
I already know that the red colour may not develop because if it turns red, this means that it was phenacetin in the powder.
Do you have any idea why its violet and not yellow or something else?
This identification is by colour, do you think this is an adventage that they do an identification by a colour reaction and not for example by spectrophotometry?
Kind regards
L. VDS
Dear Laurence,
Actually I'm a clinical toxicologist managing poisoning cases, and not so familiar with laboratory tests.
Good luck,
Nastaran
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