Why in iron deficiency anemia or chronic liver disease, erythrocyte osmotic fragility is decreased?

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María J Tuñón

See this paper:

Alterations in the erythrocyte plasma membranes in patients with alcohol induced liver cirrhosis – preliminary results. Gwoździński L et al. Arch Med Sci. 2011;7(1):87-91.

Pradipesh Chakrabarty

I am fully agree with Preeti Shanbag.For your interest you can see encyclopedia on osmotic fragility of erythrocytes. Thanks.

Md Babu Mia

Osmotic fragility depends upon surface to volume ratio. In different diseased condition, they differ a lot. Kindly follow the attached links for little more information.

http://www.academicjournals.org/journal/AJBR/article-full-text-pdf/AB649E611104

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000700009