I am preparing for endocrine hormone lecture , I read a fact about the role of GH on muscle and fatty tissues to reduce glucose uptake by these tissues and increase glucose production by the liver .
GH is a fasting hormone become active during sleeping that is why we recommend children sleep early, the the peak of this hormone during sleep is from 12 am to 4 am, also become active during exercise that needs source of energy (glucose). I n malnourished children it was recommended to give them growth GH next to a balanced diet to help lean body mass.
Growth hormone is involved in the regulation of blood glucose. It exerts anti-insulin activity by suppressing insulin’s ability to promote glucose uptake in the peripheral tissues. It also increases gluconeogenesis in the liver.
When glucagon and epinephrine fail to adequately raise blood glucose levels, the body releases cortisol and growth hormone, which can also increase blood glucose levels.