Evaluation of neuropharmacological activity of plant extract using behavioral models like (EPM, Hole board, Hole cross, Forced swim and Tail suspension test) is it mandatory to use same route for precise result?
As we know that, all groups within one experiment should always receive drugs via the same route of administration, according to the same treatment scheme and of the same volume.
But a lot of references are available where two different routes were used.
Dear,
The pharmacokinetic and pharmacodynamic aspects of drugs limit their routes of administration. In herbal medicine research, the most frequent traditional route of using considered as the best route of administration in research.However, you can test and compare different routes.Moreover, you can use oral tablet-form of diazepam in your research.
Good luck
Because of erratic absorption of oral diazepam and fluctuated plasma level
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