One of the most striking differences that has emerged so far is in the death rates of men and women.
1. The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males.
2.women have two X chromosomes, whereas men have only one – which is important when it comes a coronavirus. “In particular, the protein by which viruses such as coronavirus are sensed is encoded on the X chromosome. this protein is expressed at twice the dose on many immune cells in females compared to males, and the immune response to coronavirus is therefore amplified in females.
3.There are important behavioural differences between the sexes, for example in smoking, which affect the level of pre-existing disease such as heart disease, chronic lung disease and cancer.
4. Job and work, men are often hit harder than women in terms of unemployment. This is because more men work in industries that are closely tied to economic cycles – such as construction and manufacturing. Women, conversely, dominate more in industries not tied to such cycles, such as healthcare and
Hi Dear doctor Zeytoon
COVID-19 kills more men than women. The immune system may be why
Biological differences in how the immune system operates could help explain the mortality bias
Male patient in a hospital
As the coronavirus sweeps the globe, many countries are reporting that men fare worse with COVID-19 than women do.One theory is that women’s immune response to the virus is stronger, says Philip Goulder, professor of immunology at the University of Oxford. “The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males,” he says.
Hi Dear doctor Zeytoon
COVID-19 kills more men than women. The immune system may be why
Biological differences in how the immune system operates could help explain the mortality bias
Male patient in a hospital
As the coronavirus sweeps the globe, many countries are reporting that men fare worse with COVID-19 than women do.One theory is that women’s immune response to the virus is stronger, says Philip Goulder, professor of immunology at the University of Oxford. “The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males,” he says.
Hi Dr.
can read this p
https://www.google.com/url?sa=t&source=web&cd=1&ved=2ahUKEwiuo_KdgpLpAhUlwqYKHa4OBJsQFjAAegQIAhAB&url=https%3A%2F%2Fwww.bbc.com%2Ffuture%2Farticle%2F20200409-why-covid-19-is-different-for-men-and-women&usg=AOvVaw31486cV7bkc_-5tXVBjp3s
Hello Dr.
The novel coronavirus tends to affect men more severely than it does women. Though nobody can yet explain the oddity, researchers are hot on the case.
It's possible that the sex hormones estrogen and testosterone play a role, according to previous research on respiratory illnesses. Or perhaps it's because the X chromosome (which women have two of, but men have only one) has a larger number of immune-related genes, giving women a more robust immune system to fight off the coronavirus, SARS-CoV-2. Or, maybe the virus is hiding in the testes, which has abundant expression of ACE2 receptors, the portal that allows SARS-CoV-2 into cells.
Uncovering the real reason is, of course, imperative because it could help improve patient "outcomes during an active public health crisis," according to an editorial published April 10 in the Western Journal of Emergency Medicine (WJEM).
This is partly down to the fact that women have two X chromosomes, whereas men have only one – which is important when it comes a coronavirus. Another possibility is that the difference is down to gender-based lifestyle choices, the sex differential in smoking is especially marked in some countries such as China, where 50% of men smoke, compared to 5% in women.
https://www.google.com/url?sa=t&source=web&cd=1&ved=2ahUKEwiuo_KdgpLpAhUlwqYKHa4OBJsQFjAAegQIAhAB&url=https%3A%2F%2Fwww.bbc.com%2Ffuture%2Farticle%2F20200409-why-covid-19-is-different-for-men-and-women&usg=AOvVaw31486cV7bkc_-5tXVBjp3s
The Centers for Disease Control and Prevention (CDC) currently isn’t reporting COVID-19 deaths by gender, but experts see no reason the trend would differ elsewhere in the country.
“Some of the underlying reasons why COVID-19 may be more deadly for men than women may include the fact that heart disease is more common in elderly men than in elderly women,” Dr. Stephen Berger, an infectious disease expert and co-founder of the Global Infectious Diseases and Epidemiology Network (GIDEON), told Healthline. “Studies also find that high blood pressure and liver disease are more prevalent in men and these all contribute to more negative outcomes with COVID-19.”
I thing it concer with sex chromosome (as women have (two X chromosome) in addtion the women immune response to virus infections stronger than men
“The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males .
Alson The X chromosome influences the immune system by acting on many other proteins, including TLR8, CD40L and CXCR3 which can be over-expressed in women, and influence the response to viral infections and vaccinations.
https://www.bbc.com/future/article/20200409-why-covid-19-is-different-for-men-and-women.
Article Coronavirus COV-19/SARS-CoV-2 affects women less than men: c...
Hi dear doctor . In this paper, sufficient reasons are shown
https://www.sciencealert.com/geneticist-explains-why-more-men-are-dying-from-covid-19-than-women
Dear Dr.
I agree with Dr. https://www.researchgate.net/profile/Hamze_Abdillahi2
https://www.google.com/url?sa=t&source=web&rct=j&url=https://www.npr.org/sections/goatsandsoda/2020/04/10/831883664/the-new-coronavirus-appears-to-take-a-greater-toll-on-men-than-on-women&ved=2ahUKEwi7xLTLppLpAhWOGuwKHcS1BLsQFjAJegQIChAB&usg=AOvVaw20X0Dqmx7I1E5XQ1A41E5p.
https://www.researchgate.net/deref/https%3A%2F%2Fwww.google.com%2Furl%3Fsa%3Dt%26source%3Dweb%26rct%3Dj%26url%3Dhttps%3A%2F%2Fwww.npr.org%2Fsections%2Fgoatsandsoda%2F2020%2F04%2F10%2F831883664%2Fthe-new-coronavirus-appears-to-take-a-greater-toll-on-men-than-on-women%26ved%3D2ahUKEwi7xLTLppLpAhWOGuwKHcS1BLsQFjAJegQIChAB%26usg%3DAOvVaw20X0Dqmx7I1E5XQ1A41E5p
Hello dr
Good afternoon
May be no differences between men and wemen
Hi
One theory is that women’s immune response to the virus is stronger, says Philip Goulder, professor of immunology at the University of Oxford. “The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males,” he says.
This is partly down to the fact that women have two X chromosomes, whereas men have only one – which is important when it comes a coronavirus. “In particular, the protein by which viruses such as coronavirus are sensed is encoded on the X chromosome,” says Goulder. “As a result, this protein is expressed at twice the dose on many immune cells in females compared to males, and the immune response to coronavirus is therefore amplified in females.”
Another possibility is that the difference is down to gender-based lifestyle choices. “There are important behavioural differences between the sexes, for example in smoking, which affect the level of pre-existing disease such as heart disease, chronic lung disease and cancer,” says Goulder. “These have a huge impact on the outcome from infections such as coronavirus.
Hi Dr.
Good afternoon
https://www.sciencealert.com/geneticist-explains-why-more-men-are-dying-from-covid-19-than-women
Hi
https://www.bbc.com/future/article/20200409-why-covid-19-is-different-for-men-and-women
hi
some studies said that the female is more resistant to infection
Hi Dr.
Covid-19 tends to affect men more severely than it does women. Though nobody can yet explain the oddity, researchers are hot on the case. It's possible that the sex hormones estrogen and testosterone play a role, according to previous research on respiratory illnesses. Or perhaps it's because the X chromosome (which women have two of, but men have only one) has a larger number of immune-related genes, giving women a more robust immune system to fight off the coronavirus, SARS-CoV-2. Or, maybe the virus is hiding in the testes, which has abundant expression of ACE2 receptors, the portal that allows SARS-CoV-2 into cells.
may be because of the difference of hormones between the men and women
https://www.sciencealert.com/geneticist-explains-why-more-men-are-dying-from-covid-19-than-women
Hi dear Dr.
https://www.healthline.com/health-news/men-more-susceptible-to-serious-covid-19-illnesses
https://www.researchgate.net/deref/https%3A%2F%2Fwww.bbc.com%2Ffuture%2Farticle%2F20200409-why-covid-19-is-different-for-men-and-women
Hi doctor
There are several reason : first idea is the immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males,
Second idea is the protein by which viruses such as coronavirus are sensed is encoded on the X chromosome. As a result, this protein is expressed at twice the dose on many immune cells in females compared to males . Third idea is gender-based lifestyle
Hi dear Dr. Zeytoon
Experts say that, biology as well as behavior may be among the reasons more men than women are developing COVID-19 and dying from the disease.
Experts say part of the reason is women tend to have stronger immune systems than men.
They add that men also tend to engage in more risky behavior such as ignoring physical distancing, and they don’t take symptoms as seriously.
BR
Dear Dr.Zeytoon
There are different "theories" to explain that ,In addition to the interpretation of Dr.Hussein Oleiwi , I find that very interesting theory that the “COVID-19 appears to follow the trend of previous infections with SARS and MERS [in that] men are affected more often than women,".There are a long way and hard efforts to understand the behavior of this virus which is still surprising the globe.
Regards
Hi Dr .
Many reasons such as
1. The immune response throughout life to vaccines and infections is typically more aggressive and more effective in females compared to males.
2.women have two X chromosomes, whereas men have only one – which is important when it comes a coronavirus. “In particular, the protein by which viruses such as coronavirus are sensed is encoded on the X chromosome. this protein is expressed at twice the dose on many immune cells in females compared to males, and the immune response to coronavirus is therefore amplified in females.
3.There are important behavioural differences between the sexes, for example in smoking, which affect the level of pre-existing disease such as heart disease, chronic lung disease and cancer.
4. Job and work, men are often hit harder than women in terms of unemployment. This is because more men work in industries that are closely tied to economic cycles – such as construction and manufacturing. Women, conversely, dominate more in industries not tied to such cycles, such as healthcare.
Gender differences in immunity could be the reason, as women have stronger immune responses than men.
COVID 19 virus uses two cellular host proteins
Firstly , ACE2 protein for entry of virus into the host
Secondly, TMPRSS-2 for the Spike (S) protein priming and it also exhibits a male predominance in terms of morbidity and mortality.
TMPRSS-2 gene is upregulated by androgen hormones, and these hormones are predominantly male hormones.
Thus it is plausible that androgen-driven TMPRSS2 expression among men may explain the sex discrepancy in this disease.
I think it related to the difference between immune systems, the higher smoking rate in men than in women, and because men are less cautious compared to women.
One possible explanation may include the following: although to a lesser extent in current generations, men tend to have more risky behaviors throughout life, which probably translate, in older generations, into comorbidities that increase the lethality of the virus... On the other hand, women, who traditionally assume the role of caregivers (at home, of children, etc), have a greater relationship and attention to health issues, being more preventive and proactive in relation to themselves and the others...
Women’s bodies exhibit better resistance to fighting infections, thanks to hormones and many genes of immune functions that are based on the X chromosomes (and men only have one X chromosome). ”This means that women usually have stronger immune responses than men.
Studies a find that high blood pressure and liver disease are more prevalent in men and these all contribute to more negative results with COVID-19.
See this link, which is titled:
Gender Differences in Patients With COVID-19: Focus on Severity and Mortality
https://www.frontiersin.org/articles/10.3389/fpubh.2020.00152/full
Zeytoon Alkhafaji
Men remain more susceptible to COVID-19 than women because of the high concentration of ACE2 in their blood. Thus, women's bodies are better at fighting infection, thanks to the hormones they have and the genes in the X chromosome. It is known that the interaction of the male body with the Corona virus differs from that of the female in relation to immune, hormonal and genetic factors.
Please also take a look at this RG link.
Article COVID-19 and Individual Genetic Susceptibility/Receptivity: ...
In general, the men display higher mortality than women, which could be due to one or more underlying health risk factors, like smoking and drinking alcohol. Though there are individual differences in immune response, women appear to have a stronger immune system than men.
In general , physiological and genetic and behavioral differences between male and female
Men exposed more and prevalence of chronic diseases is more among men too. Smoking is another factor too.
You may follow the link below for better understanding:
Article Sex- and Gender-specific Observations and Implications for COVID-19
Article Are Men More Vulnerable to Covid-19 as Compared to Women?
Women's bodies show better resistance to fighting infection, thanks to hormones from the genes for immune function that are based on the X chromosomes (women have only one X chromosome). Men are more likely to get COVID-19, due to the higher concentration of angiotensin converting enzyme 2 (ACE2) in their blood. Men are more likely to get COVID-19, due to the higher concentration of angiotensin converting enzyme 2 (ACE2) in their blood.
Older age and a high number of comorbidities were associated with higher severity and mortality in patients with both COVID-19 and SARS. Age was comparable between men and women in all data sets. In the case series, however, men's cases tended to be more serious than women's (P = 0.035). In the public data set, the number of men who died from COVID-19 is 2.4 times that of women (70.3 vs. 29.7%, P = 0.016). In SARS patients, the gender role in mortality was also observed. The percentage of males were higher in the deceased group than in the survived group (P = 0.015).
Conclusion: While men and women have the same prevalence, men with COVID-19 are more at risk for worse outcomes and death, independent of age.
- Several studies have shown that more men are dying from COVID-19 than women.
- Experts say part of the reason is women tend to have stronger immune systems than men.
- They add that men also tend to engage in more risky behavior such as ignoring physical distancing, and they don’t take symptoms as seriously.
All data and statistics are based on publicly available data at the time of publication. Some information may be out of date. Visit our coronavirus hub and follow our live updates page for the most recent information on the COVID-19 outbreak.
More men are dying from COVID-19 worldwide than women, and the potential reasons run the gamut from biology to bad habits.
A study published last month in Frontiers in Public Health reported that men and women were equally likely to contract the novel coronavirus.
- Women make up 70% of all health and social-services staff globally.
- Domestic, sexual and gender-based violence increases during crises.
- Women earn just 79 cents for every dollar men make.
Given that the COVID-19 crisis affects men and women in different ways, measures to resolve it must take gender into account. For women and girls, vulnerabilities in the home, on the front lines of health care, and in the labor market must be addressed.
Regardless of where one looks, it is women who bear most of the responsibility for holding societies together, be it at home, in health care, at school, or in caring for the elderly. In many countries, women perform these tasks without pay. Yet even when the work is carried out by professionals, those professions tend to be dominated by women, and they tend to pay less than male-dominated professions.
The COVID-19 crisis has thrown these gender-based differences into even sharper relief. Regional frameworks, multilateral organizations, and international financial institutions must recognize that women will play a critical role in resolving the crisis, and that measures to address the pandemic and its economic fallout should include a gender perspective.
We see three areas where women and girls are particularly at risk and in need of stronger protections in the current crisis.
Please follow the link below:
Preprint Impact of Sex and Gender on COVID-19 Outcomes in Europe
Because a lot of studies have shown that women wear a mask more than men since maks is the primary barrier for cross-infection from person-to-person.
