Antioxidants have often been used to protect against free radicals by scavenging oxygen or ending radical chain reactions. One of the promising sources of natural antioxidants is barberry fruits. Many studies on chemical composition of barberry extract shows that the main components of barberry extract are alkaloid constituents with an isoquinolinic nucleus such as berberine, berbamine and palmatin. Conventional extraction techniques based on organic solvents have been applied to the extraction of natural antioxidants from the plant sources but those are very expensive, long time extraction period and baneful effect on product. Encapsulation is the best way to maintain the antioxidant properties of barberry.