Human possesses consciousness, intelligence, conscience, the basis for improvement. When the connection of these bases is broken, the Person begins to die. So, first of all, "Grief from the Mind" comes for Human.
Another important addition. At the core of the worldview of each Person there must be a sincere understanding of the love for each person of God who sacrificed his life for the salvation of people. Please read the Bible. Unfortunately, many people often think first of all only about themselves. And they are proud of their successes, and not the successes of others. This is the beginning of the death of Human.