I am trying to develop a periodontitis model in my lab. I read articles which demonstrate etiher experimental ligature induced models or Lipopolysaccheride induced model. Within Ligature induced model some tie knots on inferior incisor of rats and some on first or second molar teeth. Kindly suggest me that which is the best method to select and start my experiments among three mentioned above. Best Regards
The silk ligature is a proven model. There are a lot of studies which use it , so you can refer to them or compare you results at the discussion...
Dear Prof Stefan
Thanks for your valuable suggestion, i want to develop this modal also in my lab. As, i was working in an institute where we have lots of new natural and synthetic compounds to test against different diseases.
If its possible for you kindly send me video demonstration of the ligature induced periodontitis if you are practicing this in your lab in usual basis.
I will be very thankful to you in this regards.
Best Wishes
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