Considering the total contents of a cell or tissue lysate (of your liking), would the lysate contain more proteins or metabolites? I have an impression it contains more protein than metabolites. Thanks RSG.
If you wanted to compare the numbers of the kinds of proteins and metabolites in a cell, I would say that it contains more kinds of proteins than metabolites in the case of yeast cells. As far as I know, there are about 1000 kinds of metabolites and more than 6000 kinds of gene products in yeast cells.
If you wanted to compare the total numbers of protein molecules and metabolite molecules in a cell, I have no idea about that.
Depends if you ask about molarity or mass, i am fairly sure by mass proteins should be more abundant. I terms of molarity i also have no idea.
Yeah I guess I am asking about the molarity since I am asking how much of each would be a lysate with a fixed volume. Thanks for your answers guys. I think we're on the right track!
I'd still be interested if anyone has an answer for the molarity aspect of this question.
Is this connected to your query?:
https://www.ncbi.nlm.nih.gov/pubmed/25613900
http://www.wishartlab.com/projects/the-human-metabolome-project
http://www.hmdb.ca/
Good luck!, regards, + Salut
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