MTHFR mutation 677 and 1298 has relationship with so many diseases including miscarriage, infertility, neural baby defects. I understand folic acid should not work in this case. does l-methylfolate work better than folic acid?
In case of MTHFR mutation, during pregnancy l-methyfolate is better than folic acid, so far I saw in different sites
Definetly L-methylfolate
No doubt l-methylfolate has incomparably better bioavailability
But problem is doctors are not using it clinically. Still there is no recommendation from any country
http://www.omicsonline.org/open-access/folic-acid-supplementation-in-prevention-of-neural-tube-defects-2161-038X-1000e121.php?aid=59819
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