We are looking to purchase an estrogen receptor alpha (ERα) antagonist for in vivo animal studies, and ICI 182,780 appears to be a good choice. Tocris offers 50 mg of ICI for $1,119, while MedChemExpress (MCE) sells the same amount for only $159 (https://www.medchemexpress.com/Fulvestrant.html?srsltid=AfmBOoqdvEAYH7EoGIc7Vlvo9Qyw5O1-seQ97xbgUkEwpRB1eoIlwmb6).
MCE seems to provide a significantly more affordable option with comparable purity and documentation. Has anyone used either or both products for intraperitoneal (IP) or subcutaneous injections? What has your experience been?