MODELLER website's "difficult tutorial", available at link below, makes mention and use of "mGenThreader" software. Problem is: provided website by tutorial where mGenThreaded should be doesn't has the option to use mGenThreader, neither I've found any website for which I can download it. Instead of it, I've found "GenThreader" and "pGenThreader".
So I ask: Where Can I download mGenThreader? If this is not possible, may I use pGenThreader in place of mGenThreader?
https://salilab.org/modeller/tutorial/difficult.html
Dear Inacio, I think mGenThreader and GenThreader are the same thing: you need to create an alignment file as input and you can do it online: http://bioinf.cs.ucl.ac.uk/psipred/
if it doesn't work I suggest you to get in touch with the developer of GenThreader Prof David Jones at UCL ( [email protected]) I hope this help
Dear Inacio,
As recommended on the GenThreader website, I would use pGenThreader
"This method is now our recommended method for fold recognition and identification of distant homologues. Essentially it is the based on the original GenTHREADER method, but makes use of profile-profile alignments and predicted secondary structure (using PSIPRED) as inputs. This increases both the sensitivity of the method and enhances the accuracy of alignments, but also makes it much slower than the normal GenTHREADER method as PSI-BLAST needs to be run on the target sequence before the search can begin."
- Badges
- Science topic
- Similar topics
- Computer Science and Engineering
- Software