Detecting brain cancer with convolutional neural network(CNN): How to choose hyperparameters (i.e.number of filters, filter shape, max-pooling shape)?

Hi everyone, I've decided to detect brain cancer form an image library, so I wanna use the CNN algorithm to extract features from the library and train my neural network but still I wanna know how...

19 August 2020 3,734 3 View

What is an appropriate time interval for correlation of annual SPEI time series?

Hi! I'm comparing two 50-year SPEI (Standardized Precipitation Evapotranspiration Index) time series created from model and observed data (1950-1999) and averaged over a large area. Both time...

14 October 2019 1,459 3 View

Is it possible to calculate the average pore width using DFT-model?

I have tried to calculate/estimate the average pore size using DFT-model asuming slit formed pores. I am using the ASAP 2020 instrument but the instrument only gives me the total volume of the...

30 June 2019 8,406 3 View

Are there known factors/parameters affecting the sialylation/desialylation of recombinant glycoproteins produced in cell cultures?

Can a human recombinant glycoprotein produced in mammalian cell culture lose part of its sialic acid residues due to changing conditions in the culture or the purification of the protein? Any...

17 May 2019 9,954 3 View

How do I interpret a summary ROC curve with maj. of pts in up right?

Hi I am reviewing a figure for a senior member of my group and getting confused on the sROC or summary ROC curve. It is a meta analysis data set The sROC curve points are nearly all up in the...

03 April 2018 2,901 0 View

Why can't I detect p-Akt bands in my western blots?

I am looking for phospho-Akt (serine 473) in rat heart tissue samples using western blots. I have done trouble shooting for weeks but still nothing. At first we thought it was our antibodies that...

06 June 2016 4,922 5 View

What is the best tissue homogenization method for reverse lectin ELISA?

Our initial plan is to use streptavidin or neutravidin coated 96-well plates (15115, Thermo Scientific) and biotinylated lectins to isolate glycoproteins from complex samples then probe for...

10 June 2015 7,426 2 View

How much tissue of a mouse heart is sufficient for protein extraction?

Does anyone know how much tissue is needed of a mouse heart to obtain sufficient protein for western blotting? We would like to cut a mouse heart longitudinally and use one half for blots and the...

24 March 2015 7,681 7 View

Can anyone recommend a method for Mining Gene Expression Omnibus (GEO) for the expression of 1 gene?

17 October 2014 3,008 5 View

Does anyone have experience in TNF-alpha detection: ELISA vs Western Blots?

Good day For my MSc I wanted to determine the levels of TNF-a released by H9c2 cells in response to treatment with Doxorubicin. I treated every day for 5 days, so after each day I collected the...

06 August 2014 2,818 18 View

How climate change will influences human and animal behavioral change?

The role of climate change influencing the human behavior as well as economics interest

01 June 2021 0 0 View

What are the countries most affected by extreme rainfall as a result of climate change?

Increased heat, drought and insect outbreaks, all associated to climate change, have increased wildfires. Decreasing water supplies, declined agricultural yields, health impacts in cities owing to...

01 March 2021 7,168 9 View

What are the harmful effects of these extreme rainfall on the health of newborns? What are the reasons for that?

Extreme rainfall associated with climate change is causing harm to babies in some of the most forgotten places.

01 March 2021 5,647 4 View

How to arrange coordinates and extract climate dataset out of MPI-ESM-MR netcdf files?

Have a nice day everyone, I'm stuck in extracting datasets out of MPI-ESM-MR netcdf files because the latitude ranges from -3*10^6 to 3*10^6 and longitude ranges -5,9*10^6 to 5,9*10^6. Plus, the...

28 February 2021 912 3 View

Can we recognize signs of the "volatility clustering" property of a time series in its time domain plot?

My purpose is to recognize the volatility clustering property without statistical tests such as The Lagrange Multiplier (LM) test.

24 February 2021 4,150 3 View

Could the "incoming radiation (net radiation)" values be negative?

Could the "incoming solar radiation" values be negative? What is the difference between "global solar radiation" and "incoming solar radiation"? Which one might be measured negative values?

21 February 2021 7,726 9 View

Is the box plot of climatic indices better illustrate from daily data or annual data?

Hello, I hope you have a good time. I work on a research project about temperature indices. Due to the high number of indices, I only work on tables and maps on an annual time scale. In other...

19 February 2021 9,742 2 View

Historical wind data/map?

Hello All, I am looking for the historical wind data/map (mainly the year 2020-2021). I would like to look at the wind value and direction for the specifics locations within the US for the...

18 February 2021 9,543 4 View

What are the LAB methodologies (procedures, equipment etc) for CO2 enrichment experiments to study crop responses?

I am doing a proposal for a research entitled 'GRAIN YIELD AND QUALITY RESPONSES OF WHEAT GENOTYPES UNDER CO2 ENRICHMENT AND EXTREME EVENTS' I will be using climate chamber and I would like to...

18 February 2021 6,494 4 View

What are the recently methods to estimate low-flow and high-flow time series in ungauged basins?

Hi Is there any new method to estimate ( predict ) low-flow and high-flow regimes in daily scales for ungauged hydrometric stations? Thanks

15 February 2021 3,493 3 View