Have these particles been observed in predicted places?
For example, have scientists ever noticed the creation of energy and
pair particles from nothing in the Large Electron–Positron Collider,
Large Hadron Collider at CERN, Tevatron at Fermilab or other
particle accelerators since late 1930? The answer is no. In fact, no
report of observing such particles by highly sensitive sensors used in
all accelerators has been mentioned.
Moreover, according to one interpretation of uncertainty
principle, abundant charged and uncharged virtual particles should
continuously whiz inside the storage rings of all particle accelerators.
Scientists and engineers make sure that they maintain ultra-high
vacuum at close to absolute zero temperature, in the travelling path
of the accelerating particles otherwise even residual gas molecules
deflect, attach to, or ionize any particle they encounter but there has
not been any concern or any report of undesirable collisions with so
called virtual particles in any accelerator.
It would have been absolutely useless to create ultrahigh vacuum,
pressure of about 10-14 bar, throughout the travel path of the particles
if vacuum chambers were seething with particle/antiparticle or
matter/antimatter. If there was such a phenomenon there would have
been significant background effects as a result of the collision and
scattering of the beam of accelerating particles from the supposed
bubbling of virtual particles created in vacuum. This process is
readily available for examination in comparison to totally out of
reach Hawking’s radiation which is considered to be a real
phenomenon that will be eating away supposed black holes of the
universe in a very long future.
for related issues/argument see
Preprint SCIENCE IN THE SHADOW OF METAPHYSICS Part 2 -The Issue of Existence