In general sense, all the drugs have an expiry date (shelf life). After the expiry date the drug is recommended not to use as it may produce toxic effects in biological system and/or lose its potency in lesser or greater extent i.e. deviation from the optimum specification is seen. My question is what will be happened in case of a toxicant (toxin)? Is there any recommendation for toxiants' using? What will be there toxicological efficacy after expiry?