What Ultrasonic Method Is Recommended for Dissolving Brequinar in DMSO?

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I am planning to dissolve Brequinar (HY-108325) at a concentration of 25 mg/mL in DMSO before mixing it with Aquaphor. Could anyone recommend an appropriate ultrasonic method for this dissolution process? Any specific parameters or tips that could enhance the solubility would be greatly appreciated!

Hongya Cheng

Hi，

Ultrasonic cleaning instrument，20-40 kHz, temperature 37-50 ℃.

Ultrasonic time: 1-3 min each time, repeat several times, and observe the state of the solution.

The answer to this question is provided by MedChemExpress Technical Support.

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