What type cellophaneuse membrane(specificatins) should be d to perform drug diffusion study of Insitu ophthalmic gel using Franz diffusion cell?

Vishnu Prabhakar Choudhari @Vishnu_Choudhari3

02 February 2016 1 2K Report

I am working on Insitu ophthalmic gel containing two drugs with molecular weight about 500 and 350. I need to decide the type of cellophane membrane.

Rahul Umakant Hude

for ophthalmic gel to perform in-vitro diffusion study cellophane membrane having pore size 0.22-0.45 micron should be used; having membrane Molecular weight cut-off (MWCO) 10000-18000.

https://www.thermofisher.com/in/en/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/protein-biology-application-notes/separation-characteristics-dialysis-membranes.html

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