I can't find a solvent to extract my product from DMSO? I used a lot of solvent, the problem is that the solvent is miscible with DMSO or my product is not soluble in this solvent.
If your product is not soluble in water then addition of water will precipitate out your compound. Then you just need a simple filtration
If your product is not soluble in a solvent that is miscible with DMSO, the addition of this solvent in the system probably will precipitate your product (not mentioned in your question). then you can filtrate and re-dissolve your product.
Hi,
Try to evaporate DMSO and redisolve the compound in other solvent. If you cannot do that and need to extract the compound try with diethylether if you didn't.
Good luck
Hi,
The problem is that i can't evaoprate DMSO because my product is not stable thermally (at the boiling point of DMSO 189°C), and for the extraction with diethylether, my product is more soluble in DMSO than in diethyether so my product prefers DMSO phase than phase diethyl ether.
Why do you need to extract the product from DMSO? Could I know what product is?
Cannot you try to evaporate under vacuum, thus lowering the temperature? Otherwise you could try to recover by SPE or similar. I send you some links that could be useful for your aim:
http://webbook.nist.gov/cgi/cbook.cgi?ID=C823825&Units=SI&Mask=2000#Gas-Chrom
http://www.chemspider.com/Chemical-Structure.63172.html
I'm sorry I cannot help you more. Good luck
Add the rxn mixture to water, cool to 20 - 25 °C then add toluene to the RM, after extracting in toluene wash with 10% sodium chloride soln. (DMSO is immiscible with Toluene).
If your product is not soluble in water then addition of water will precipitate out your compound. Then you just need a simple filtration
u can evaporate DMSO at low temperature using a genevac system (30ºC), you can also use an SPE filtration with resine.
Hi,
Add 3 to 4 times of water and extract with ether or ethyl acetate
The usual way is, to avoid DMSO as solvent. Because DMSO solves nearly every solvent you can try to remove DMSO e.g. in high vacuo and resolve your sample in the desired solvent.
the answer by Maria Koyioni · 18.15 · 21.65 · University of Cyprus
is the simplest way to do it
The addition of water and a neutral electrolite, like NaCl will help to extract an organic solute with ether or ethyl acetate.
vaporization the DMSO to the smallest quantity then add cold water (2 fold) if clear solution without ppt, you can make extraction by ethyl acetate
If your product was solid and has B.P greater than DMSO you can remove it by evaporation method by using Kogl Rohr evaporation.
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