What separation method do you recommend for separating pyrotechol from hydroquinone?

Hossein Salehi Vanani @Hossein-Salehi-Vanani

22 January 2024 1 9K Report

Pyroteccol and hydroquinone are two phenolic isomers that differ in the position of the hydroxy group.

Hydroquinone is a non-polar compound and pyrotechol is a polar compound, but both dissolve in many solvents due to hydrogen bonding.

Bruce Neagle

Try using Isopropanol alcohol in your mobile phase and a C18 HPLC column with a UV detector.

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