Hi all,
I'm looking for molecules (molecular weight > 400 g/mol) soluble in both water and non-polar oils, such as cyclohexane.
I hope the molecule is partitioned in each phase (water and non-polar oil).
Please let me know if you know any of them.
Thanks!
Many emulsifying agents are soluble in both. Something like mono-laurin which is ~300 daltons should do the trick. However, you may run into some trouble with your partition as they will help form an emulsion which may not settle into separate phases.
The solubility depends on the functional groups of the molecule and at what concentration is it needed to be soluble. Based on the logP value you can determine the solubility. Also you may want to bracket the upper value of the molecular weight. A good start would be the amphoteric compounds.
I suggest that you check also this related RG discussion:
https://www.researchgate.net/post/Are_there_dyes_that_are_soluble_in_both_oil_and_water
Hi Baekmin Kim!
Polyethylene glycol / polyethylene oxide (PEO) are soluble in water and chloroform / dichloromethane (see the attached file). I worked with them during my master.
Rogério.
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